Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 918837..919393 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EL066_RS04375 Protein ID WP_126480465.1
Coordinates 918837..919127 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL066_RS04380 Protein ID WP_126480467.1
Coordinates 919115..919393 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS04355 913884..914834 - 951 WP_126480458.1 acetyltransferase -
EL066_RS04360 914831..916576 - 1746 WP_126480460.1 IucA/IucC family siderophore biosynthesis protein -
EL066_RS04365 916714..917937 + 1224 WP_126480461.1 MFS transporter -
EL066_RS04370 917943..918827 + 885 WP_126480463.1 siderophore-interacting protein -
EL066_RS04375 918837..919127 - 291 WP_126480465.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL066_RS04380 919115..919393 - 279 WP_126480467.1 CopG family ribbon-helix-helix protein Antitoxin
EL066_RS04385 919479..919865 - 387 WP_126480469.1 oxalurate catabolism protein HpxZ -
EL066_RS04390 919869..921269 - 1401 WP_126480471.1 AtzE family amidohydrolase -
EL066_RS04395 921266..921457 - 192 WP_126480473.1 oxalurate catabolism protein HpxX -
EL066_RS04400 921482..923068 - 1587 WP_126480475.1 gamma-glutamyltransferase family protein -
EL066_RS04405 923213..924052 + 840 WP_126480477.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10920.65 Da        Isoelectric Point: 10.1818

>T286860 WP_126480465.1 NZ_LR134151:c919127-918837 [Serratia plymuthica]
VPQLIWTPAALLDVQRLYRFLAEKDLNSAKRAVATIRNSIKIIAHQPHIGRPAKDMAPEFREWPVDFGNSGYLVMYRFNG
VTAVILAIRHQSETGY

Download         Length: 291 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10676.75 Da        Isoelectric Point: 4.9380

>AT286860 WP_126480467.1 NZ_LR134151:c919393-919115 [Serratia plymuthica]
MATATSIKIDDELKQRVQHIAATRQRSAHWIMREAIREYVEREEKREAVRNDALQAWETYQANGKHLTQDEADGWLSDLE
KGDDTEIPGCHN

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References