286830

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 970391..971043 Replicon chromosome
Accession NZ_LR134136
Organism Atlantibacter hermannii strain NCTC12129

Toxin (Protein)


Gene name ypjF Uniprot ID H5V7Q7
Locus tag EL032_RS04590 Protein ID WP_002438660.1
Coordinates 970391..970705 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID H5V7Q6
Locus tag EL032_RS04595 Protein ID WP_002438659.1
Coordinates 970726..971043 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL032_RS04565 (NCTC12129_01045) 965423..966677 + 1255 Protein_894 glutamate-5-semialdehyde dehydrogenase -
EL032_RS04575 (NCTC12129_01048) 967278..968279 + 1002 WP_002438595.1 BsuBI/PstI family type II restriction endonuclease -
EL032_RS04580 (NCTC12129_01049) 968329..969858 - 1530 WP_002438597.1 Eco57I restriction-modification methylase domain-containing protein -
EL032_RS04585 (NCTC12129_01050) 969991..970251 - 261 Protein_897 restriction endonuclease subunit M -
EL032_RS04590 (NCTC12129_01051) 970391..970705 - 315 WP_002438660.1 TA system toxin CbtA family protein Toxin
EL032_RS04595 (NCTC12129_01052) 970726..971043 - 318 WP_002438659.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL032_RS04600 (NCTC12129_01053) 971062..971283 - 222 WP_000691995.1 DUF987 domain-containing protein -
EL032_RS04605 (NCTC12129_01054) 971292..971768 - 477 WP_002438657.1 RadC family protein -
EL032_RS04610 (NCTC12129_01055) 971784..972242 - 459 WP_002438656.1 antirestriction protein -
EL032_RS04615 972351..972578 - 228 WP_081479374.1 DUF905 domain-containing protein -
EL032_RS04620 972741..973274 - 534 Protein_904 DeoR family transcriptional regulator -
EL032_RS04625 (NCTC12129_01057) 973491..974312 - 822 WP_002438653.1 DUF932 domain-containing protein -
EL032_RS04630 (NCTC12129_01058) 974404..975268 - 865 Protein_906 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 969898..1019092 49194


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11636.46 Da        Isoelectric Point: 6.4533

>T286830 WP_002438660.1 NZ_LR134136:c970705-970391 [Atlantibacter hermannii]
MKTLPATTPQAAKLCLPPVAVWQMLLARLLEQHYGLTLNDTSFSDETVIQEHIDAGITLADAVNFLVDKYELVRIDRRGL
SWQAQSSYLRAVDILRARQATGLL

Download         Length: 315 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11953.51 Da        Isoelectric Point: 6.6244

>AT286830 WP_002438659.1 NZ_LR134136:c971043-970726 [Atlantibacter hermannii]
MSNITWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECQKLDETFPHFISQIESMLTTYELNPRHAHCVILYH
NGFTCEADTLGSCGYVYVAVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H5V7Q7

Antitoxin

Source ID Structure
AlphaFold DB H5V7Q6

References