Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4618070..4618652 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL015_RS21070 Protein ID WP_005186844.1
Coordinates 4618362..4618652 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0T9ML19
Locus tag EL015_RS21065 Protein ID WP_032906763.1
Coordinates 4618070..4618351 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS21045 4613195..4614049 + 855 WP_005186854.1 formate dehydrogenase accessory sulfurtransferase FdhD -
EL015_RS21050 4614174..4614794 + 621 WP_032906754.1 superoxide dismutase [Mn] -
EL015_RS21055 4615189..4617150 + 1962 WP_005186851.1 methyl-accepting chemotaxis protein -
EL015_RS21060 4617294..4617968 + 675 WP_005186847.1 6-N-hydroxylaminopurine resistance protein -
EL015_RS21065 4618070..4618351 + 282 WP_032906763.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL015_RS21070 4618362..4618652 + 291 WP_005186844.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL015_RS21075 4618718..4619074 - 357 WP_005186841.1 YibL family ribosome-associated protein -
EL015_RS21080 4619167..4620648 - 1482 WP_032906752.1 PLP-dependent aminotransferase family protein -
EL015_RS21085 4620864..4621472 + 609 WP_032906751.1 LysE family translocator -
EL015_RS21090 4621474..4622028 - 555 WP_005186837.1 MltR family transcriptional regulator -
EL015_RS21095 4622210..4623373 - 1164 WP_005186836.1 mannitol-1-phosphate 5-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-96)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11249.86 Da        Isoelectric Point: 6.8695

>T286817 WP_005186844.1 NZ_LR134116:4618362-4618652 [Yersinia intermedia]
MPRTADYTKDFLKDWERLSRSGRYDMYRLKHAMLLLIANDTPLGAEWLDHPLKGDWENFRECHIGGDFLLIYKLSSSSKI
SQIIFVRAGTHSELFD

Download         Length: 291 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10371.76 Da        Isoelectric Point: 5.0859

>AT286817 WP_032906763.1 NZ_LR134116:4618070-4618351 [Yersinia intermedia]
MATHTTMLHVRIDDDVKKQATAALNAMGLSVSDAVRLFLNRVVADQAFPFELKVPNPQTRAAMQEAEEIVQAHSARFTTS
DELFIELEKDNSK

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9ML19

References