Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 4080837..4081537 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag EL015_RS18640 Protein ID WP_005186647.1
Coordinates 4081166..4081537 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag EL015_RS18635 Protein ID WP_032906673.1
Coordinates 4080837..4081169 (-) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS18620 4077961..4078758 - 798 WP_005186659.1 tetratricopeptide repeat protein -
EL015_RS18625 4079009..4079683 - 675 WP_005186657.1 DUF2625 domain-containing protein -
EL015_RS18630 4079892..4080752 - 861 WP_005186655.1 DUF4942 domain-containing protein -
EL015_RS18635 4080837..4081169 - 333 WP_032906673.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL015_RS18640 4081166..4081537 - 372 WP_005186647.1 TA system toxin CbtA family protein Toxin
EL015_RS18645 4081673..4082158 - 486 WP_005186643.1 DNA repair protein RadC -
EL015_RS18650 4082178..4082609 - 432 WP_005186639.1 antirestriction protein -
EL015_RS18655 4082965..4083786 - 822 WP_032906671.1 DUF945 domain-containing protein -
EL015_RS18660 4083935..4084372 - 438 WP_005186633.1 hypothetical protein -
EL015_RS18665 4084429..4084983 - 555 WP_005186631.1 hypothetical protein -
EL015_RS18670 4085287..4086171 - 885 WP_126286801.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-101)

Antitoxin

Antitoxin CbeA

(9-108)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13746.84 Da        Isoelectric Point: 7.3134

>T286816 WP_005186647.1 NZ_LR134116:c4081537-4081166 [Yersinia intermedia]
MKPRPTSPGALPVPIIYQQLLAFLLEHYYGLSLNDTPYHDEQVIAQQIEREISVGDTINALVDKYVLVRIGRNGFSALAQ
DPMLSKGDIARARQAAGLWRAHFPPTLLYPTESLNPIPQRPLT

Download         Length: 372 bp

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12089.76 Da        Isoelectric Point: 6.7475

>AT286816 WP_032906673.1 NZ_LR134116:c4081169-4080837 [Yersinia intermedia]
MNNHMTTSPTWGLQCDITPRLGARLVQEGTHLHFLSDRAHIVGTFSLEATQALDAAFPALITKLESQLLSGALDPRRQQG
ITVRHGEFVCEADTLGSHGYLYIAVYQKLA

Download         Length: 333 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References