Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1323921..1324456 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL015_RS06155 Protein ID WP_032905972.1
Coordinates 1324169..1324456 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0T9M846
Locus tag EL015_RS06150 Protein ID WP_032905973.1
Coordinates 1323921..1324172 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS06125 1319348..1319851 + 504 WP_032905979.1 ferredoxin-type protein NapF -
EL015_RS06130 1319841..1320107 + 267 WP_032905977.1 chaperone NapD -
EL015_RS06135 1320104..1322599 + 2496 WP_032905975.1 nitrate reductase catalytic subunit NapA -
EL015_RS06140 1322695..1323162 + 468 WP_032905974.1 nitrate reductase cytochrome c-type subunit -
EL015_RS06145 1323191..1323790 + 600 WP_005183830.1 cytochrome c-type protein NapC -
EL015_RS06150 1323921..1324172 + 252 WP_032905973.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL015_RS06155 1324169..1324456 + 288 WP_032905972.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL015_RS06160 1324486..1325061 + 576 WP_032906016.1 GDP-mannose pyrophosphatase NudK -
EL015_RS06165 1325397..1327676 + 2280 WP_005183822.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
EL015_RS06170 1327763..1328218 - 456 WP_032905970.1 YaiI/YqxD family protein -
EL015_RS06175 1328218..1329144 - 927 WP_005183819.1 oxygen-dependent coproporphyrinogen oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.05 Da        Isoelectric Point: 10.3510

>T286809 WP_032905972.1 NZ_LR134116:1324169-1324456 [Yersinia intermedia]
MTYAVKFREEALKEWHKLDKTIQQQFAKKLKKCSDNPHIESAKLRGMKNCYKIKLRSSGFRLVYEIIDDVLIVAVVAVGK
RDRSEVYNLASDRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.56 Da        Isoelectric Point: 4.3287

>AT286809 WP_032905973.1 NZ_LR134116:1323921-1324172 [Yersinia intermedia]
MPSIILTDTSASVSELKKNPMATVNAGAGFPVAILNRNQPAFYCVPAELYEQIMEALDDHELAELVNRRRHQPLLDIDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9M846

References