Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 897771..898446 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name cptA Uniprot ID A0A0T9MA63
Locus tag EL015_RS04150 Protein ID WP_032908006.1
Coordinates 898018..898446 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A0T9M975
Locus tag EL015_RS04145 Protein ID WP_005193092.1
Coordinates 897771..898037 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS04125 893931..894680 + 750 WP_005193105.1 SDR family oxidoreductase -
EL015_RS04130 894742..895350 - 609 WP_005193102.1 HD domain-containing protein -
EL015_RS04135 895705..896355 + 651 WP_005193099.1 hemolysin III family protein -
EL015_RS04140 896413..897405 - 993 WP_005193095.1 tRNA-modifying protein YgfZ -
EL015_RS04145 897771..898037 + 267 WP_005193092.1 FAD assembly factor SdhE Antitoxin
EL015_RS04150 898018..898446 + 429 WP_032908006.1 protein YgfX Toxin
EL015_RS04155 898443..899138 + 696 WP_032908003.1 two-component system response regulator CreB -
EL015_RS04160 899166..900593 + 1428 WP_032906548.1 two-component system sensor histidine kinase CreC -
EL015_RS04165 900686..902092 + 1407 WP_005185995.1 cell envelope integrity protein CreD -
EL015_RS04170 902143..902661 - 519 WP_005185992.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 16529.42 Da        Isoelectric Point: 10.3815

>T286808 WP_032908006.1 NZ_LR134116:898018-898446 [Yersinia intermedia]
VAQWRCDLRVSWHTQLFSLLSHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNITSCQGEIRLKPGNLVLWKRL
EWIVVKQPWITRYGVLLNLQQSSSRSARKRLWLAADSMSEDEWRQLCLLLRHSFGSDKGMNQ

Download         Length: 429 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10462.96 Da        Isoelectric Point: 5.1405

>AT286808 WP_005193092.1 NZ_LR134116:897771-898037 [Yersinia intermedia]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQAFIRLLECDDPDLFNWLMNHGEPQDSELRQMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0T9MA63

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9M975

References