Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 652733..653199 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name relE Uniprot ID A0A0T9MGJ2
Locus tag EL015_RS02995 Protein ID WP_032906934.1
Coordinates 652733..653008 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0T9MGP0
Locus tag EL015_RS03000 Protein ID WP_032906933.1
Coordinates 653008..653199 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS02980 647757..650024 + 2268 WP_005188260.1 DNA topoisomerase IV subunit A -
EL015_RS02985 650247..650987 + 741 WP_005188255.1 1-acylglycerol-3-phosphate O-acyltransferase -
EL015_RS02990 651159..652586 + 1428 WP_005188253.1 cell division protein FtsP -
EL015_RS02995 652733..653008 - 276 WP_032906934.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
EL015_RS03000 653008..653199 - 192 WP_032906933.1 hypothetical protein Antitoxin
EL015_RS03005 653370..655640 + 2271 WP_005188248.1 YgiQ family radical SAM protein -
EL015_RS03010 655662..656495 - 834 WP_005188245.1 2,5-didehydrogluconate reductase DkgA -
EL015_RS03015 656812..657969 - 1158 WP_005188243.1 alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10442.91 Da        Isoelectric Point: 4.7385

>T286807 WP_032906934.1 NZ_LR134116:c653008-652733 [Yersinia intermedia]
MLPIKWTDEAKTDLYALIAFITEENPYAAESLLHQLEDSVLPATEHPYMFRSGRVPGTREIVAHPNYVIIYQVMADQISV
LNVVHSRQEYP

Download         Length: 276 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7164.16 Da        Isoelectric Point: 7.0117

>AT286807 WP_032906933.1 NZ_LR134116:c653199-653008 [Yersinia intermedia]
MSTKLSPIVSEFETEEQAESYDLWFRAKVEASMNSPKPQTPHDEVMAGARKIIEQAKARRKLA

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0T9MGJ2

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9MGP0

References