Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 606268..606990 Replicon chromosome
Accession NZ_LR134116
Organism Yersinia intermedia strain NCTC11469

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag EL015_RS02780 Protein ID WP_005190380.1
Coordinates 606670..606990 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag EL015_RS02775 Protein ID WP_032907452.1
Coordinates 606268..606603 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL015_RS02760 601922..603628 - 1707 WP_032907453.1 hypothetical protein -
EL015_RS02765 603612..605354 - 1743 WP_005190390.1 hypothetical protein -
EL015_RS02770 605775..606254 + 480 WP_005190387.1 DNA repair protein RadC -
EL015_RS02775 606268..606603 + 336 WP_032907452.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL015_RS02780 606670..606990 + 321 WP_005190380.1 TA system toxin CbtA family protein Toxin
EL015_RS02785 607104..607943 + 840 WP_005190376.1 DUF4942 domain-containing protein -
EL015_RS02795 608330..610168 - 1839 WP_005190373.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 603612..613972 10360


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12054.72 Da        Isoelectric Point: 6.0591

>T286806 WP_005190380.1 NZ_LR134116:606670-606990 [Yersinia intermedia]
MQISTVPATVLVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDASIQEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQQQTPFLTATDILRAKRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12542.34 Da        Isoelectric Point: 6.3149

>AT286806 WP_032907452.1 NZ_LR134116:606268-606603 [Yersinia intermedia]
MNKDATQTWGLKRDITPCFGARLVQEGHRLHFLADRAGFNVSFSEMQARDLEEAFPHFVAHMELMLLSGELNPWCAHCVT
LYRNGLTCEADTLGSYGYVYIAIYPSNLVKA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References