Detailed information of TA system TA028679

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 3781773..3782536
• Replicon: chromosome
• Accession: NC_019940
• Organism: Thioflavicoccus mobilis 8321

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: THIMO_RS16415
• Protein ID: WP_041604670.1
• Coordinates: 3782042..3782536 (+)
• Length: 165 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: L0H3F0
• Locus tag: THIMO_RS16410
• Protein ID: WP_015282241.1
• Coordinates: 3781773..3782045 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (28-148)

Antitoxin

• Vibrio phage ICP1, Orf50 (3-87)

Sequences

Toxin

Protein

• Length: 165 a.a.
• Molecular weight: 17733.31 Da
• Isoelectric Point: 8.9724

>T28679 WP_041604670.1 NC_019940:3782042-3782536 [Thioflavicoccus mobilis 8321]
ISRLLSAPHPLAAAHVLDEFACGEASLDEWLKRRALTNQLSGASRTFVVSDQDGRVQGYYAMAAGAVSHQAATSAVRRNM
PDPVPVMVLARLSIDHRAQGIKLGGALLQDAVHRAVAVSQNAGVRALLVHALHDHAKAFYEHYGFQASPLHPMTLMLRLH
AHEP

Nucleotide

• Length: 495 bp

>T28679 NC_019940:3782042-3782536 [Thioflavicoccus mobilis 8321]
ATAAGCAGGCTCTTGAGCGCGCCGCACCCCCTCGCGGCCGCCCACGTCCTGGACGAGTTCGCCTGCGGGGAGGCCAGCCT
CGATGAATGGCTCAAACGCCGGGCATTGACGAACCAGTTGAGCGGCGCAAGCCGCACCTTCGTCGTCAGCGATCAGGACG
GGCGTGTCCAGGGCTACTACGCGATGGCCGCAGGTGCGGTTTCACACCAAGCCGCCACCAGTGCCGTGCGCCGCAACATG
CCTGACCCGGTGCCCGTGATGGTGCTCGCGAGGCTATCCATCGATCATCGCGCCCAAGGCATCAAGCTGGGCGGGGCCTT
GCTGCAGGACGCGGTTCATCGGGCTGTGGCGGTCTCGCAAAACGCCGGGGTTCGGGCGCTGCTGGTGCACGCGCTCCACG
ACCACGCCAAGGCGTTCTACGAGCATTACGGTTTTCAGGCGTCGCCGCTCCATCCGATGACGCTGATGTTGCGGCTCCAT
GCGCACGAGCCATGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9873.29 Da
• Isoelectric Point: 5.0175

>AT28679 WP_015282241.1 NC_019940:3781773-3782045 [Thioflavicoccus mobilis 8321]
MRDAAINLRALPEQRDLIDHAASLLGKSRSEFMLEAACDRARSVVLDQVFFSLDADKFQQFTAMLDAPPSPNPGLERLMA
VKAPWNTGGA

Nucleotide

• Length: 273 bp

>AT28679 NC_019940:3781773-3782045 [Thioflavicoccus mobilis 8321]
ATGCGTGATGCCGCCATCAATCTACGGGCGCTGCCTGAGCAGCGTGATCTGATCGATCACGCGGCCAGCCTGCTCGGTAA
AAGCCGGTCTGAATTCATGCTCGAAGCGGCCTGCGACCGAGCACGGTCCGTGGTGCTGGATCAGGTCTTTTTCAGCCTGG
ACGCAGACAAGTTCCAGCAATTCACCGCGATGCTCGATGCGCCTCCGAGCCCCAACCCCGGGCTTGAACGCCTGATGGCC
GTCAAAGCACCGTGGAACACCGGCGGGGCATAA

Structures

Antitoxin

• AlphaFold DB: L0H3F0