Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2206903..2207174 Replicon chromosome
Accession NZ_LR134092
Organism Escherichia coli strain NCTC10444

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2207033..2207136 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2206903..2207174 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL041_RS10655 2203458..2204120 - 663 WP_000944256.1 exodeoxyribonuclease X -
EL041_RS10660 2204144..2204800 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EL041_RS10665 2204902..2205132 - 231 WP_000916760.1 DNA polymerase III subunit theta -
EL041_RS10670 2205271..2205645 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL041_RS10675 2205649..2206521 + 873 WP_000879287.1 copper homeostasis membrane protein CopD -
EL041_RS10680 2206534..2206875 + 342 WP_000976472.1 YebY family protein -
- 2206903..2207174 - 272 - - Antitoxin
- 2207033..2207136 + 104 - - Toxin
EL041_RS10685 2207271..2207927 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
EL041_RS10690 2207928..2208119 - 192 WP_001313035.1 YebW family protein -
EL041_RS10695 2208224..2208460 - 237 WP_001295499.1 DUF1480 family protein -
EL041_RS10700 2208578..2210017 - 1440 WP_001695829.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286764 NZ_LR134092:2207033-2207136 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286764 NZ_LR134092:c2207174-2206903 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References