28676

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2972015..2973500 Replicon chromosome
Accession NC_019940
Organism Thioflavicoccus mobilis 8321

Toxin (Protein)


Gene name rlegT Uniprot ID L0GZK5
Locus tag THIMO_RS12835 Protein ID WP_015281533.1
Coordinates 2972015..2972890 (-) Length 292 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID L0H012
Locus tag THIMO_RS12840 Protein ID WP_015281534.1
Coordinates 2972883..2973500 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
THIMO_RS12825 2969998..2970714 - 717 WP_015281531.1 condensin subunit E -
THIMO_RS12830 2970711..2972018 - 1308 WP_086014999.1 condensin subunit MukF -
THIMO_RS12835 2972015..2972890 - 876 WP_015281533.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
THIMO_RS12840 2972883..2973500 - 618 WP_015281534.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
THIMO_RS12845 2973701..2974921 + 1221 WP_157633764.1 hypothetical protein -
THIMO_RS12850 2975153..2976748 - 1596 WP_015281536.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(10-56)


Sequences

Toxin        


Download         Length: 292 a.a.        Molecular weight: 32503.02 Da        Isoelectric Point: 4.7378

>T28676 WP_015281533.1 NC_019940:c2972890-2972015 [Thioflavicoccus mobilis 8321]
MPREIRNVGASVRARLQNLSRETGQSFELILTRYALERLLYRLSTSAFSDRFVLKGAMLLTSWFTDPHRATRDLDLLGFG
DPSPEAMAAAFQEILAIDVEDGVEFDSNAVRVDLIREEFEYGGLRLRTTASISGARIAVTVDVAFGDALEPGAEVIDYPC
MLDLPAPRLRAYARETVIAEKFQAMVALGRANSRMKDFYDIWLLSQSFPFDDNRLARAIAATFERRETEIPADLPDALTP
AFAEDEQKRRQWSAFLENVALRPGSLPEVIEGVARFLMPHAIAAAKLGRSD

Download         Length: 876 bp

>T28676 NC_019940:c2972890-2972015 [Thioflavicoccus mobilis 8321]
ATGCCTAGGGAGATCAGAAACGTCGGCGCCTCCGTTCGGGCGCGTCTGCAGAATCTCTCTCGAGAAACGGGACAGAGTTT
CGAGCTGATACTCACCCGCTATGCGTTGGAACGCCTGCTTTACCGTCTCAGCACGTCGGCCTTCTCCGACCGATTCGTGC
TCAAGGGCGCGATGCTGCTGACGAGCTGGTTTACGGATCCACACCGGGCTACGCGTGATCTCGACCTGTTGGGATTCGGC
GATCCAAGCCCGGAGGCGATGGCTGCAGCATTCCAGGAGATTCTCGCGATCGACGTCGAGGATGGCGTCGAATTCGATTC
GAACGCGGTACGTGTCGACCTGATCCGGGAGGAGTTCGAGTACGGCGGACTGCGGCTGCGCACGACCGCATCGATCAGTG
GTGCCCGTATCGCTGTAACAGTCGACGTCGCATTCGGAGACGCGTTGGAGCCGGGTGCCGAGGTCATCGACTACCCGTGC
ATGCTGGACCTTCCCGCACCTCGCCTGCGCGCCTACGCCCGCGAAACGGTGATTGCCGAGAAATTCCAGGCAATGGTGGC
GCTTGGGCGCGCGAACAGCCGAATGAAGGACTTCTATGACATTTGGCTCCTCAGCCAGTCGTTTCCGTTCGACGACAACC
GGCTTGCCCGCGCAATCGCCGCGACCTTCGAACGGCGCGAGACCGAGATCCCGGCGGACCTGCCGGATGCCCTTACGCCG
GCCTTTGCCGAGGATGAGCAGAAGCGGCGTCAGTGGAGTGCTTTTCTGGAGAACGTGGCGCTTCGTCCCGGCAGCCTACC
TGAGGTGATCGAAGGTGTTGCCCGATTCCTCATGCCTCACGCCATCGCCGCAGCGAAGCTCGGCAGGAGCGATTGA

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22275.97 Da        Isoelectric Point: 10.6764

>AT28676 WP_015281534.1 NC_019940:c2973500-2972883 [Thioflavicoccus mobilis 8321]
MAKPRAQRELAQNLLKKQGIMRLLELREAGVTAATMSRMERAGEVIRLSRGVYQLPDADLDPNHSLAEAAKRVPKGIVCL
VSALAFHGLTDQLPPKVWMAIGPKDWAPQRSGAGIRIVRFTDSLLREGIETHVIEGVSVKVFGVAKTVADCFRHRGKVGL
SVAIEGLQEALRQRKATPAEIARQAEKGGVSTVVRPYLEALTANA

Download         Length: 618 bp

>AT28676 NC_019940:c2973500-2972883 [Thioflavicoccus mobilis 8321]
ATGGCAAAGCCCCGAGCGCAGCGTGAGCTCGCCCAAAACCTGCTGAAGAAGCAGGGAATCATGCGCCTGCTCGAGCTGCG
CGAGGCCGGCGTGACCGCGGCGACCATGAGTCGTATGGAGCGGGCCGGCGAAGTCATCCGCCTGTCGCGGGGCGTCTATC
AGCTGCCAGATGCCGACCTCGACCCCAATCACAGCCTGGCGGAGGCCGCGAAGCGGGTGCCCAAGGGCATCGTATGTCTC
GTCTCGGCGTTGGCATTCCACGGTCTGACCGACCAGCTACCGCCGAAAGTCTGGATGGCGATCGGACCCAAGGACTGGGC
GCCGCAGCGCAGCGGTGCGGGCATCCGCATTGTGCGTTTCACAGACAGCCTGCTGAGGGAGGGCATCGAAACACACGTGA
TCGAAGGCGTGTCGGTGAAAGTCTTCGGCGTGGCCAAGACGGTGGCCGATTGCTTCCGACATCGCGGCAAAGTGGGCCTG
TCCGTCGCGATCGAGGGCCTCCAGGAGGCGCTGAGGCAACGCAAGGCGACTCCGGCGGAAATTGCTCGTCAAGCCGAGAA
GGGCGGGGTATCCACAGTCGTGCGGCCGTATCTCGAGGCACTGACCGCCAATGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB L0GZK5

Antitoxin

Source ID Structure
AlphaFold DB L0H012

References