Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 401954..402708 Replicon chromosome
Accession NZ_LR134092
Organism Escherichia coli strain NCTC10444

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag EL041_RS01880 Protein ID WP_001301452.1
Coordinates 401954..402439 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EL041_RS01885 Protein ID WP_000801914.1
Coordinates 402430..402708 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL041_RS01860 397121..397879 + 759 WP_000815099.1 DeoR/GlpR family transcriptional regulator -
EL041_RS01865 397861..399459 - 1599 WP_126297721.1 DNA-binding transcriptional regulator RtcR -
EL041_RS01870 399646..400872 + 1227 WP_001105465.1 RNA-splicing ligase RtcB -
EL041_RS01875 400876..401904 + 1029 WP_024257792.1 RNA 3'-terminal phosphate cyclase -
EL041_RS01880 401954..402439 - 486 WP_001301452.1 GNAT family N-acetyltransferase Toxin
EL041_RS01885 402430..402708 - 279 WP_000801914.1 DUF1778 domain-containing protein Antitoxin
EL041_RS01890 402775..405480 - 2706 WP_000906970.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-143)

Antitoxin

Vibrio phage ICP1, Orf50

(2-92)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17650.57 Da        Isoelectric Point: 9.4066

>T286758 WP_001301452.1 NZ_LR134092:c402439-401954 [Escherichia coli]
MGITAPTPLTSEHNLADFCCSDHGMNEWLKKKALKNHSSGLSRVYVICIANTRQVIGYYCLSTGSIQRNLAPGAMRRNAP
ESLPVVVLGRLAIDQAWAGKGLGVALLKDAVYRTMSIAQQVGVRALIVHALDDSVRNFYLKYAFVPSPFQSLTLLYPITL
E

Download         Length: 486 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10406.91 Da        Isoelectric Point: 4.6336

>AT286758 WP_000801914.1 NZ_LR134092:c402708-402430 [Escherichia coli]
MKPESKEAPINIRAKASQRDLIDMAANLVAKSRTDFMLDAACREAQDILLDQRLFIVDDEQYDAFLAALDAPITAERQAK
INALMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References