Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3611278..3612161 Replicon chromosome
Accession NC_019905
Organism Pseudomonas putida HB3267

Toxin (Protein)


Gene name - Uniprot ID A0A0C1HTG7
Locus tag B479_RS16415 Protein ID WP_015270851.1
Coordinates 3611278..3611715 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag B479_RS16420 Protein ID WP_013973163.1
Coordinates 3611712..3612161 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B479_RS16395 3606506..3607570 + 1065 WP_015270847.1 TerC family protein -
B479_RS16400 3607648..3608877 - 1230 WP_015270848.1 acyl-CoA dehydrogenase -
B479_RS16405 3609018..3609944 + 927 WP_015270849.1 LysR family transcriptional regulator -
B479_RS16410 3610116..3611270 + 1155 WP_015270850.1 aminotransferase class V-fold PLP-dependent enzyme -
B479_RS16415 3611278..3611715 - 438 WP_015270851.1 RES family NAD+ phosphorylase Toxin
B479_RS16420 3611712..3612161 - 450 WP_013973163.1 DUF2384 domain-containing protein Antitoxin
B479_RS16425 3612260..3612913 - 654 WP_015270852.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
B479_RS16430 3613018..3613941 + 924 WP_015270853.1 LysR family transcriptional regulator -
B479_RS16435 3613989..3614819 + 831 WP_015270854.1 AraC family transcriptional regulator -
B479_RS16440 3614870..3615454 + 585 WP_015270855.1 LysE family translocator -
B479_RS16445 3615594..3616793 - 1200 WP_043935712.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15969.19 Da        Isoelectric Point: 5.1199

>T28666 WP_015270851.1 NC_019905:c3611715-3611278 [Pseudomonas putida HB3267]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Download         Length: 438 bp

>T28666 NC_019905:c3611715-3611278 [Pseudomonas putida HB3267]
GTGATTCTGTGGCGTATCAGCGCCTATGCAGACTTGAGCGGAACGGGCGGCTTGCGTGTCAGCGGCCGCTGGCACCAGGC
GGGCCGGCCAGTGGTATATGCCGCCACCAGCCCGGCCGGGGCAATGCTGGAGGTGCTGGTGCACCTGGAGATCGACCCTG
AGGATTTCCCCACCACCATGCGGCTGCTGCGTATCGAGTTGCCCGACACCGTTTCGCAAGCGCAGTTGCCCGCCTTGCAG
CCTGGCTGGTCGAGCCAGACCGAACTGACCCGGGGCCTGGGCAACCGTTTTCTGGATGAGTGTTCGGCGTTGCTGCTGCC
GGTGCCGAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCGCGCCATCCGCAGGCAAACAGCGCCAGGCTCG
AGGTCGAGGACTTCACCCCGGACAGCCGGCTGTTTTAG

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT28666 WP_013973163.1 NC_019905:c3612161-3611712 [Pseudomonas putida HB3267]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp

>AT28666 NC_019905:c3612161-3611712 [Pseudomonas putida HB3267]
ATGCTTGCCGAAGTGCTTCGCGACAATGGTTACCACGAGTACCGGGCGCGCCTGCATGCACTGCTGGAAATCCCCGAACT
CGCCAGTGACTTCGAAATCCACACCCGTATCACCCATGGCTTCGCTGCCACCTGGCTGGTGAAACTGACCGAACTCGGCG
TGTTCACCCCTGTGGAGCGTGACCAGATCATTCCCCTGCGCACGCTGAAAACCCGCATCGAACGTGACCAGCCGCTGACC
GTGGAAGAAAGTGACCGGCTGTTCCGCTCGGCCCATATCACCGCCATGGCCGAAGCCGTGTTCGGTGAAGCGGGCAAGGC
AAAACGCTGGCTGTCCAAGCCCAAGGAGCGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAGGGCACCA
CCCAGGTCGAGGAGATGTTGCTGCAGATCGCCGAGGGCTTCGGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C1HTG7

Antitoxin

Source ID Structure
AlphaFold DB F8G488

References