Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2074689..2074960 Replicon chromosome
Accession NZ_LR134080
Organism Escherichia coli strain NCTC9082

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2074819..2074922 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2074689..2074960 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL023_RS10130 2071244..2071906 - 663 WP_000944260.1 exodeoxyribonuclease X -
EL023_RS10135 2071930..2072586 - 657 WP_115189031.1 carbon-nitrogen hydrolase family protein -
EL023_RS10140 2072688..2072918 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL023_RS10145 2073057..2073431 + 375 WP_024243787.1 CopC domain-containing protein YobA -
EL023_RS10150 2073435..2074307 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
EL023_RS10155 2074320..2074661 + 342 WP_000976492.1 YebY family protein -
- 2074689..2074960 - 272 - - Antitoxin
- 2074819..2074922 + 104 - - Toxin
EL023_RS10160 2075057..2075713 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EL023_RS10165 2075714..2075905 - 192 WP_001296140.1 YebW family protein -
EL023_RS10170 2076010..2076246 - 237 WP_001295499.1 DUF1480 family protein -
EL023_RS10175 2076364..2077803 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286655 NZ_LR134080:2074819-2074922 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286655 NZ_LR134080:c2074960-2074689 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References