Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2244352..2244623 Replicon chromosome
Accession NZ_LR134079
Organism Escherichia coli strain NCTC9112

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2244482..2244585 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2244352..2244623 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL053_RS11185 2240907..2241569 - 663 WP_000944256.1 exodeoxyribonuclease X -
EL053_RS11190 2241593..2242249 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EL053_RS11195 2242351..2242581 - 231 WP_000916760.1 DNA polymerase III subunit theta -
EL053_RS11200 2242720..2243094 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL053_RS11205 2243098..2243970 + 873 WP_000879287.1 copper homeostasis membrane protein CopD -
EL053_RS11210 2243983..2244324 + 342 WP_000976472.1 YebY family protein -
- 2244352..2244623 - 272 - - Antitoxin
- 2244482..2244585 + 104 - - Toxin
EL053_RS11215 2244720..2245376 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
EL053_RS11220 2245377..2245568 - 192 WP_001313035.1 YebW family protein -
EL053_RS11225 2245673..2245909 - 237 WP_001295499.1 DUF1480 family protein -
EL053_RS11230 2246027..2247466 - 1440 WP_001695829.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286631 NZ_LR134079:2244482-2244585 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286631 NZ_LR134079:c2244623-2244352 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References