Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2237429..2237697 Replicon chromosome
Accession NZ_LR134031
Organism Escherichia coli strain NCTC11151

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2237557..2237659 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2237429..2237697 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL024_RS11125 2233983..2234645 - 663 WP_000944256.1 exodeoxyribonuclease X -
EL024_RS11130 2234668..2235324 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
EL024_RS11135 2235426..2235656 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL024_RS11140 2235795..2236169 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL024_RS11145 2236173..2237045 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
EL024_RS11150 2237058..2237399 + 342 WP_000984819.1 YebY family protein -
- 2237429..2237697 - 269 - - Antitoxin
- 2237557..2237659 + 103 - - Toxin
EL024_RS11155 2237794..2238450 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
EL024_RS11160 2238451..2238642 - 192 WP_001296140.1 YebW family protein -
EL024_RS11165 2238747..2238983 - 237 WP_001295499.1 DUF1480 family protein -
EL024_RS11170 2239101..2240540 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286587 NZ_LR134031:2237557-2237659 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCTTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT286587 NZ_LR134031:c2237697-2237429 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAAGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References