Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1979282..1979553 Replicon chromosome
Accession NZ_LR134000
Organism Escherichia coli strain NCTC9066

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1979412..1979515 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1979282..1979553 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL014_RS09605 1975837..1976499 - 663 WP_000944242.1 exodeoxyribonuclease X -
EL014_RS09610 1976523..1977179 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
EL014_RS09615 1977281..1977511 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL014_RS09620 1977650..1978024 + 375 WP_000255065.1 CopC domain-containing protein YobA -
EL014_RS09625 1978028..1978900 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EL014_RS09630 1978913..1979254 + 342 WP_000976472.1 YebY family protein -
- 1979282..1979553 - 272 - - Antitoxin
- 1979412..1979515 + 104 - - Toxin
EL014_RS09635 1979650..1980306 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
EL014_RS09640 1980307..1980498 - 192 WP_001338167.1 YebW family protein -
EL014_RS09645 1980603..1980839 - 237 WP_001338166.1 DUF1480 family protein -
EL014_RS09650 1980957..1982396 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286564 NZ_LR134000:1979412-1979515 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286564 NZ_LR134000:c1979553-1979282 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References