Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1851584..1851729 Replicon chromosome
Accession NZ_LR133964
Organism Klebsiella pneumoniae strain NCTC11359

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1851620..1851722 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1851584..1851729 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL047_RS09165 1846714..1848774 + 2061 WP_126438534.1 oligopeptidase B -
EL047_RS09170 1848778..1849437 - 660 WP_002911407.1 exodeoxyribonuclease X -
EL047_RS09175 1849516..1849746 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EL047_RS09180 1849859..1850233 + 375 WP_126438535.1 CopC domain-containing protein YobA -
EL047_RS09185 1850237..1851106 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
EL047_RS09190 1851123..1851461 + 339 WP_016529031.1 YebY family protein -
- 1851584..1851729 - 146 - - Antitoxin
- 1851620..1851722 + 103 - - Toxin
EL047_RS25340 1852096..1852239 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EL047_RS09200 1852344..1853312 - 969 WP_004151446.1 VirK/YbjX family protein -
EL047_RS09205 1853469..1854122 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
EL047_RS09210 1854119..1854310 - 192 WP_002911395.1 YebW family protein -
EL047_RS09215 1854408..1854647 - 240 WP_002911393.1 YebV family protein -
EL047_RS09220 1854763..1856196 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286530 NZ_LR133964:1851620-1851722 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT286530 NZ_LR133964:c1851729-1851584 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References