Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 704337..704988 Replicon chromosome
Accession NZ_LR131273
Organism Tsukamurella paurometabola strain NCTC10741

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ELY19_RS03640 Protein ID WP_164711501.1
Coordinates 704560..704988 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ELY19_RS03635 Protein ID WP_126194987.1
Coordinates 704337..704567 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELY19_RS03610 699778..700881 + 1104 WP_126194982.1 citrate synthase 2 -
ELY19_RS03615 700885..702009 + 1125 WP_126194983.1 phosphoserine transaminase -
ELY19_RS03620 702035..702820 + 786 WP_126194984.1 DUF3071 domain-containing protein -
ELY19_RS03625 702825..703577 + 753 WP_126194985.1 hypothetical protein -
ELY19_RS03630 703593..704246 + 654 WP_126194986.1 hypothetical protein -
ELY19_RS03635 704337..704567 + 231 WP_126194987.1 hypothetical protein Antitoxin
ELY19_RS03640 704560..704988 + 429 WP_164711501.1 PIN domain-containing protein Toxin
ELY19_RS03645 705297..706580 - 1284 WP_126194989.1 MFS transporter -
ELY19_RS03650 706617..706895 - 279 WP_126194990.1 DUF2537 domain-containing protein -
ELY19_RS03655 706892..707692 - 801 WP_126194991.1 RNA methyltransferase -
ELY19_RS03660 707723..708874 + 1152 WP_126194992.1 GNAT family N-acetyltransferase -
ELY19_RS03665 708974..709429 - 456 WP_126194993.1 MarR family transcriptional regulator -
ELY19_RS03670 709531..709740 + 210 WP_126194994.1 DUF2530 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(6-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15215.55 Da        Isoelectric Point: 6.4869

>T286501 WP_164711501.1 NZ_LR131273:704560-704988 [Tsukamurella paurometabola]
MSDVELPDVNVLVALLSANHVHHTTARDWFASTPRFATTPITEAGLVRMALNRAVMGTAITAQQALASLASLRADDRAEF
VPDESSLAAPSIDLVGLAGHKQVTDLHLVNLMARHSGVLVTLDTRIRPVLTPADQPLVRVLL

Download         Length: 429 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 7977.02 Da        Isoelectric Point: 4.6816

>AT286501 WP_126194987.1 NZ_LR131273:704337-704567 [Tsukamurella paurometabola]
VRTTLDISPRVLAAARARVNAGQNKSIGEAVSELAALGLETATASRRPTDHGLVMLPSAPDHVITSEMVEDALLDE

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References