Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) unclassified/Polyketide_cyc2(toxin)
Location 4618822..4619452 Replicon chromosome
Accession NZ_LR130759
Organism Mycobacterium basiliense isolate 901379

Toxin (Protein)


Gene name novel[antitoxin] Uniprot ID -
Locus tag MB901379_RS19485 Protein ID WP_158018106.1
Coordinates 4618822..4619259 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name novel[toxin] Uniprot ID -
Locus tag MB901379_RS19490 Protein ID WP_158018107.1
Coordinates 4619264..4619452 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MB901379_RS19460 4614123..4615343 + 1221 WP_158018103.1 acetyl-CoA acetyltransferase -
MB901379_RS19465 4615346..4616860 + 1515 WP_158018104.1 carotenoid oxygenase family protein -
MB901379_RS19470 4616923..4617381 + 459 WP_158019318.1 VOC family protein -
MB901379_RS19475 4617399..4617821 - 423 WP_158018105.1 hypothetical protein -
MB901379_RS19480 4617925..4618698 - 774 WP_158019319.1 VOC family protein -
MB901379_RS19485 4618822..4619259 - 438 WP_158018106.1 SRPBCC family protein Toxin
MB901379_RS19490 4619264..4619452 - 189 WP_158018107.1 antitoxin Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polyketide cyclase/dehydrase

(1-142)

Antitoxin

Antitoxin Rv0909/MT0933

(4-50)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15761.29 Da        Isoelectric Point: 8.5620

>T286499 WP_158018106.1 NZ_LR130759:c4619259-4618822 [Mycobacterium basiliense]
MAKLSGSIDVPLAPEEAWQHASDLSRYKDWLTIHRVWRSTLPESLEKGAVVESIVQVKGMHNRIKWTIVRYKPPEGMTLN
GDGVGGVKVKLMAKVAPKEDGSVVSFDVHLGGPALFGPIGMIVAGALRSDIRESLENFVTVFAPA

Download         Length: 438 bp

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6652.41 Da        Isoelectric Point: 6.4579

>AT286499 WP_158018107.1 NZ_LR130759:c4619452-4619264 [Mycobacterium basiliense]
MGILDKAKNLLSQNADKVETAIDKAGEFVDQKTQGKYSDTIHKVQEEAKKVAGPGAAGDQQH

Download         Length: 189 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References