Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2183798..2184069 Replicon chromosome
Accession NZ_LR130562
Organism Escherichia coli strain MS14384 isolate MS14384

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2183928..2184031 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2183798..2184069 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW037_RS10590 2180353..2181015 - 663 WP_000944256.1 exodeoxyribonuclease X -
EW037_RS10595 2181039..2181695 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
EW037_RS10600 2181797..2182027 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EW037_RS10605 2182166..2182540 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EW037_RS10610 2182544..2183416 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
EW037_RS10615 2183429..2183770 + 342 WP_000976472.1 YebY family protein -
- 2183798..2184069 - 272 - - Antitoxin
- 2183928..2184031 + 104 - - Toxin
EW037_RS10620 2184166..2184822 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
EW037_RS10625 2184823..2185014 - 192 WP_001296140.1 YebW family protein -
EW037_RS10630 2185119..2185355 - 237 WP_001295499.1 DUF1480 family protein -
EW037_RS10635 2185473..2186912 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2176488..2186918 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286457 NZ_LR130562:2183928-2184031 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286457 NZ_LR130562:c2184069-2183798 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References