Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2260368..2260639 Replicon chromosome
Accession NZ_LR130555
Organism Escherichia coli strain MS14385 isolate MS14385

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2260498..2260601 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2260368..2260639 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW040_RS10975 2256923..2257585 - 663 WP_000944256.1 exodeoxyribonuclease X -
EW040_RS10980 2257609..2258265 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
EW040_RS10985 2258367..2258597 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EW040_RS10990 2258736..2259110 + 375 WP_022645803.1 CopC domain-containing protein YobA -
EW040_RS10995 2259114..2259986 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
EW040_RS11000 2259999..2260340 + 342 WP_000976472.1 YebY family protein -
- 2260368..2260639 - 272 - - Antitoxin
- 2260498..2260601 + 104 - - Toxin
EW040_RS11005 2260736..2261392 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
EW040_RS11010 2261393..2261584 - 192 WP_001296140.1 YebW family protein -
EW040_RS11015 2261689..2261925 - 237 WP_001295499.1 DUF1480 family protein -
EW040_RS11020 2262043..2263482 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T286423 NZ_LR130555:2260498-2260601 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT286423 NZ_LR130555:c2260639-2260368 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References