Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2681351..2681619 Replicon chromosome
Accession NZ_LR130545
Organism Escherichia coli strain B36 isolate B36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2681389..2681491 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2681351..2681619 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW036_RS13430 2678509..2679948 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EW036_RS13435 2680065..2680301 + 237 WP_001295499.1 DUF1480 family protein -
EW036_RS13440 2680406..2680597 + 192 WP_001296140.1 YebW family protein -
EW036_RS13445 2680598..2681254 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 2681351..2681619 + 269 - - Antitoxin
- 2681389..2681491 - 103 - - Toxin
EW036_RS13450 2681649..2681990 - 342 WP_000976472.1 YebY family protein -
EW036_RS13455 2682003..2682875 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
EW036_RS13460 2682879..2683253 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EW036_RS13465 2683392..2683622 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EW036_RS13470 2683724..2684380 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
EW036_RS13475 2684404..2685066 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286358 NZ_LR130545:c2681491-2681389 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT286358 NZ_LR130545:2681351-2681619 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References