Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1888760..1888900 Replicon chromosome
Accession NZ_LR130543
Organism Klebsiella variicola strain 04153260899A isolate 04153260899A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1888796..1888898 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1888760..1888900 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW039_RS09280 1883890..1885950 + 2061 WP_012541258.1 oligopeptidase B -
EW039_RS09285 1885954..1886613 - 660 WP_022066251.1 exodeoxyribonuclease X -
EW039_RS09290 1886692..1886922 - 231 WP_012541260.1 DNA polymerase III subunit theta -
EW039_RS09295 1887036..1887410 + 375 WP_008804269.1 CopC domain-containing protein YobA -
EW039_RS09300 1887414..1888283 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
EW039_RS09305 1888300..1888638 + 339 WP_008804271.1 YebY family protein -
- 1888760..1888900 - 141 - - Antitoxin
- 1888796..1888898 + 103 - - Toxin
EW039_RS09310 1888976..1890061 - 1086 WP_129678578.1 phage integrase Arm DNA-binding domain-containing protein -
EW039_RS09315 1890030..1890302 - 273 WP_129678579.1 excisionase -
EW039_RS26625 1890435..1890602 - 168 WP_172601098.1 hypothetical protein -
EW039_RS09320 1890628..1891257 - 630 WP_129678580.1 Eac protein -
EW039_RS09325 1891293..1892114 - 822 WP_129678581.1 hypothetical protein -
EW039_RS09330 1892172..1892429 - 258 WP_129678582.1 DNA polymerase III subunit theta -
EW039_RS09335 1892516..1892713 - 198 WP_129678583.1 hypothetical protein -
EW039_RS09340 1892706..1893278 - 573 WP_129678797.1 DUF551 domain-containing protein -
EW039_RS09345 1893533..1893745 - 213 WP_004141386.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1883923..1956569 72646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286323 NZ_LR130543:1888796-1888898 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT286323 NZ_LR130543:c1888900-1888760 [Klebsiella variicola]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References