Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2015966..2016111 | Replicon | chromosome |
| Accession | NZ_LR130541 | ||
| Organism | Klebsiella pneumoniae strain AJ218 isolate AJ218 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2016002..2016104 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2015966..2016111 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EW045_RS10085 | 2011096..2013156 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| EW045_RS10090 | 2013160..2013819 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| EW045_RS10095 | 2013898..2014128 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| EW045_RS10100 | 2014241..2014615 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| EW045_RS10105 | 2014619..2015488 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| EW045_RS10110 | 2015505..2015843 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2015966..2016111 | - | 146 | - | - | Antitoxin |
| - | 2016002..2016104 | + | 103 | - | - | Toxin |
| EW045_RS28290 | 2016479..2016622 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| EW045_RS10120 | 2016727..2017695 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| EW045_RS10125 | 2017852..2018505 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| EW045_RS10130 | 2018502..2018693 | - | 192 | WP_002911395.1 | YebW family protein | - |
| EW045_RS10135 | 2018791..2019030 | - | 240 | WP_002911393.1 | YebV family protein | - |
| EW045_RS10140 | 2019146..2020579 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T286306 NZ_LR130541:2016002-2016104 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT286306 NZ_LR130541:c2016111-2015966 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
