Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1903802..1903946 Replicon chromosome
Accession NZ_LR130539
Organism Klebsiella variicola strain AJ055 isolate AJ055

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1903838..1903940 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1903802..1903946 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW050_RS09335 1898932..1900992 + 2061 WP_129670968.1 oligopeptidase B -
EW050_RS09340 1900996..1901655 - 660 WP_008804267.1 exodeoxyribonuclease X -
EW050_RS09345 1901734..1901964 - 231 WP_012541260.1 DNA polymerase III subunit theta -
EW050_RS09350 1902078..1902452 + 375 WP_008804269.1 CopC domain-containing protein YobA -
EW050_RS09355 1902456..1903325 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
EW050_RS09360 1903342..1903680 + 339 WP_008804271.1 YebY family protein -
- 1903802..1903946 - 145 - - Antitoxin
- 1903838..1903940 + 103 - - Toxin
EW050_RS28075 1904325..1904468 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
EW050_RS09370 1904572..1905540 - 969 WP_162493241.1 VirK/YbjX family protein -
EW050_RS09375 1905696..1906349 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
EW050_RS09380 1906346..1906537 - 192 WP_002911395.1 YebW family protein -
EW050_RS09385 1906635..1906874 - 240 WP_002911393.1 YebV family protein -
EW050_RS09390 1906990..1908423 - 1434 WP_110184966.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286290 NZ_LR130539:1903838-1903940 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT286290 NZ_LR130539:c1903946-1903802 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References