Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1878171..1878315 Replicon chromosome
Accession NZ_LR130538
Organism Klebsiella variicola strain AJ292 isolate AJ292

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1878207..1878309 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1878171..1878315 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW044_RS09245 1873301..1875361 + 2061 WP_032746815.1 oligopeptidase B -
EW044_RS09250 1875365..1876024 - 660 WP_008804267.1 exodeoxyribonuclease X -
EW044_RS09255 1876103..1876333 - 231 WP_012541260.1 DNA polymerase III subunit theta -
EW044_RS09260 1876447..1876821 + 375 WP_016161388.1 CopC domain-containing protein YobA -
EW044_RS09265 1876825..1877694 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
EW044_RS09270 1877711..1878049 + 339 WP_008804271.1 YebY family protein -
- 1878171..1878315 - 145 - - Antitoxin
- 1878207..1878309 + 103 - - Toxin
EW044_RS26710 1878694..1878837 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
EW044_RS09280 1878941..1879909 - 969 WP_162493241.1 VirK/YbjX family protein -
EW044_RS09285 1880066..1880719 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
EW044_RS09290 1880716..1880907 - 192 WP_002911395.1 YebW family protein -
EW044_RS09295 1881005..1881244 - 240 WP_002911393.1 YebV family protein -
EW044_RS09300 1881360..1882793 - 1434 WP_012967754.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T286277 NZ_LR130538:1878207-1878309 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT286277 NZ_LR130538:c1878315-1878171 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References