Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 1358211..1359469 | Replicon | chromosome |
Accession | NZ_LR130533 | ||
Organism | Pseudomonas aeruginosa isolate paerg009 |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | EJN60_RS06705 | Protein ID | WP_003086331.1 |
Coordinates | 1358211..1358966 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | EJN60_RS06710 | Protein ID | WP_003086329.1 |
Coordinates | 1359101..1359469 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EJN60_RS06695 | 1353382..1355925 | + | 2544 | WP_003108653.1 | acyl-homoserine-lactone acylase QuiP | - |
EJN60_RS06700 | 1356080..1357441 | - | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
EJN60_RS06705 | 1358211..1358966 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
EJN60_RS06710 | 1359101..1359469 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
EJN60_RS06715 | 1359542..1360828 | - | 1287 | WP_003086327.1 | FAD-binding oxidoreductase | - |
EJN60_RS06720 | 1360884..1362473 | - | 1590 | WP_003123191.1 | aldehyde dehydrogenase family protein | - |
EJN60_RS06725 | 1362552..1363028 | + | 477 | WP_004353334.1 | elongation factor GreAB | - |
EJN60_RS33495 | 1363031..1363291 | - | 261 | WP_023095977.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T286241 WP_003086331.1 NZ_LR130533:c1358966-1358211 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT286241 WP_003086329.1 NZ_LR130533:c1359469-1359101 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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