Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-yefM/Txe-RelB |
Location | 2449764..2450287 | Replicon | chromosome |
Accession | NZ_LR130511 | ||
Organism | Staphylococcus aureus strain BPH2819 isolate BPH2819 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A3A5LQI3 |
Locus tag | EW030_RS12705 | Protein ID | WP_000074049.1 |
Coordinates | 2449764..2450030 (-) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | W8TQT5 |
Locus tag | EW030_RS12710 | Protein ID | WP_000587616.1 |
Coordinates | 2450030..2450287 (-) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EW030_RS12685 | 2445071..2446258 | - | 1188 | WP_000026189.1 | MFS transporter | - |
EW030_RS12690 | 2446654..2447430 | - | 777 | WP_000072149.1 | iron export ABC transporter permease subunit FetB | - |
EW030_RS12695 | 2447423..2448085 | - | 663 | WP_000923526.1 | ATP-binding cassette domain-containing protein | - |
EW030_RS12700 | 2448333..2449409 | - | 1077 | WP_001076673.1 | M42 family metallopeptidase | - |
EW030_RS12705 | 2449764..2450030 | - | 267 | WP_000074049.1 | Txe/YoeB family addiction module toxin | Toxin |
EW030_RS12710 | 2450030..2450287 | - | 258 | WP_000587616.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EW030_RS12720 | 2450646..2451101 | + | 456 | WP_000732076.1 | DUF1307 domain-containing protein | - |
EW030_RS12725 | 2451269..2452846 | - | 1578 | WP_061644026.1 | FMN-binding glutamate synthase family protein | - |
EW030_RS12730 | 2453041..2453790 | + | 750 | WP_000072461.1 | CPBP family intramembrane metalloprotease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3A5LQI3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | W8TQT5 |