286133

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 820669..821146 Replicon chromosome
Accession NZ_LR130511
Organism Staphylococcus aureus strain BPH2819 isolate BPH2819

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag EW030_RS04095 Protein ID WP_000052076.1
Coordinates 820669..820857 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag EW030_RS04100 Protein ID WP_001059690.1
Coordinates 820886..821146 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW030_RS04065 816663..817184 + 522 WP_000824482.1 hypothetical protein -
EW030_RS04070 817525..818211 + 687 WP_000141557.1 thermonuclease family protein -
EW030_RS04075 818568..818768 + 201 WP_001059082.1 cold-shock protein -
EW030_RS04080 819260..819478 - 219 WP_000005886.1 hypothetical protein -
EW030_RS04085 819540..819824 - 285 WP_001004399.1 hypothetical protein -
EW030_RS04090 819912..820481 - 570 WP_001106654.1 hypothetical protein -
EW030_RS04095 820669..820857 - 189 WP_000052076.1 hypothetical protein Toxin
EW030_RS04100 820886..821146 - 261 WP_001059690.1 hypothetical protein Antitoxin
EW030_RS04105 821487..821690 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
EW030_RS04110 821687..821923 - 237 WP_000349581.1 hypothetical protein -
EW030_RS04115 822148..822729 + 582 WP_001140693.1 phosphoglycerate mutase family protein -
EW030_RS04120 822802..823419 - 618 WP_000255551.1 LysE/ArgO family amino acid transporter -
EW030_RS04125 823574..824068 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
EW030_RS04130 824467..824889 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
EW030_RS04135 825037..825753 + 717 WP_000150011.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T286133 WP_000052076.1 NZ_LR130511:c820857-820669 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT286133 WP_001059690.1 NZ_LR130511:c821146-820886 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References