Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1642745..1643382 Replicon chromosome
Accession NC_019779
Organism Halothece sp. PCC 7418 (Aphanothece halophytica 7418)

Toxin (Protein)


Gene name vapC Uniprot ID K9Y9T1
Locus tag PCC7418_RS07430 Protein ID WP_015225562.1
Coordinates 1642745..1643155 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID K9YB59
Locus tag PCC7418_RS07435 Protein ID WP_015225563.1
Coordinates 1643152..1643382 (-) Length 77 a.a.

Genomic Context

PCC7418_RS07420PCC7418_RS07410PCC7418_RS07415PCC7418_RS07425PCC7418_RS07430PCC7418_RS07435PCC7418_RS07440PCC7418_RS07445
Location: 1640344..1641939 (1596 bp)
Type: Others
Protein ID: WP_015225560.1
Location: 1638263..1639504 (1242 bp)
Type: Others
Protein ID: WP_150107131.1
Location: 1639562..1640257 (696 bp)
Type: Others
Protein ID: WP_015225559.1
Location: 1641906..1642712 (807 bp)
Type: Others
Protein ID: WP_015225561.1
Location: 1642745..1643155 (411 bp)
Type: Toxin
Protein ID: WP_015225562.1
Location: 1643152..1643382 (231 bp)
Type: Antitoxin
Protein ID: WP_015225563.1
Location: 1643574..1645244 (1671 bp)
Type: Others
Protein ID: WP_015225564.1
Location: 1645342..1647123 (1782 bp)
Type: Others
Protein ID: WP_015225565.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCC7418_RS074101638263..1639504-1242WP_150107131.1class I SAM-dependent RNA methyltransferase-
PCC7418_RS074151639562..1640257-696WP_015225559.1ribulose-phosphate 3-epimerase-
PCC7418_RS074201640344..1641939+1596WP_015225560.1S8 family serine peptidase-
PCC7418_RS074251641906..1642712-807WP_015225561.1SWIM zinc finger family protein-
PCC7418_RS074301642745..1643155-411WP_015225562.1type II toxin-antitoxin system VapC family toxinToxin
PCC7418_RS074351643152..1643382-231WP_015225563.1DUF2281 domain-containing proteinAntitoxin
PCC7418_RS074401643574..1645244-1671WP_015225564.1chaperonin GroEL-
PCC7418_RS074451645342..1647123-1782WP_015225565.1glycosyltransferase family 39 protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-136)

Antitoxin

Domain of unknown function DUF2281

(6-74)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15608.08 Da        Isoelectric Point: 6.6468

>T28610 WP_015225562.1 NC_019779:c1643155-1642745 [Halothece sp. PCC 7418]
MSAFLLDTHAFIWLSEDDPNLPESLREKIDKADVVYVSIASLWEIAIKLNLGKLSLKRNYEIIGIEVESSDIILLPISFR
DTALIRHLPLHHRDPFDRMLVAQAMNHSLIIASRDRAKLAGRANRAFDAYSIERIW

Download         Length: 411 bp

>T28610 NC_019779:c1643155-1642745 [Halothece sp. PCC 7418]
ATGAGTGCTTTTCTATTAGACACTCACGCTTTTATTTGGCTGTCGGAAGATGACCCAAATTTACCAGAATCCCTCAGAGA
GAAGATTGATAAAGCTGATGTTGTATATGTTAGCATCGCAAGTTTATGGGAGATTGCGATTAAGTTAAACTTGGGAAAGT
TATCTCTAAAACGAAATTATGAAATCATTGGTATTGAAGTTGAATCTTCTGACATTATTTTACTTCCTATTTCATTTCGT
GATACAGCTTTAATTCGCCACTTACCTTTACACCATCGAGATCCATTTGATCGAATGTTAGTTGCACAAGCAATGAATCA
TTCTTTAATTATAGCTAGTCGCGATCGAGCGAAGCTCGCTGGCAGAGCCAATCGCGCTTTTGATGCTTATTCAATAGAAA
GAATTTGGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9052.27 Da        Isoelectric Point: 4.6388

>AT28610 WP_015225563.1 NC_019779:c1643382-1643152 [Halothece sp. PCC 7418]
MNTDLELWQAISKMPEHLKTEFLNYAEYLMEKKANTTHSDQNLEKKRRSGILKGTFVLPLPKDFDEPLEDFQDYME

Download         Length: 231 bp

>AT28610 NC_019779:c1643382-1643152 [Halothece sp. PCC 7418]
ATGAATACTGATCTCGAACTCTGGCAAGCAATTAGCAAAATGCCTGAACATTTAAAGACTGAATTTTTGAATTATGCAGA
ATATTTAATGGAGAAAAAAGCAAACACAACTCACTCGGATCAAAACTTAGAAAAAAAACGGCGATCTGGAATTTTGAAAG
GAACTTTTGTCTTACCATTACCAAAAGACTTTGATGAACCATTAGAAGATTTTCAGGATTATATGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBK9Y9T1

Antitoxin

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Source
ID
Structure
AlphaFold DBK9YB59

References