Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1186197..1186834 Replicon chromosome
Accession NC_019779
Organism Halothece sp. PCC 7418 (Aphanothece halophytica 7418)

Toxin (Protein)


Gene name vapC Uniprot ID K9Y8M6
Locus tag PCC7418_RS05430 Protein ID WP_015225168.1
Coordinates 1186197..1186601 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag PCC7418_RS05435 Protein ID WP_041596154.1
Coordinates 1186601..1186834 (-) Length 78 a.a.

Genomic Context

PCC7418_RS05410PCC7418_RS05415PCC7418_RS05420PCC7418_RS05445PCC7418_RS05450PCC7418_RS05425PCC7418_RS05430PCC7418_RS05435PCC7418_RS05440
Location: 1182434..1182844 (411 bp)
Type: Others
Protein ID: WP_150107126.1
Location: 1182983..1183846 (864 bp)
Type: Others
Protein ID: WP_015225165.1
Location: 1183843..1185123 (1281 bp)
Type: Others
Protein ID: WP_015225166.1
Location: 1189086..1190075 (990 bp)
Type: Others
Protein ID: WP_015225171.1
Location: 1190281..1191507 (1227 bp)
Type: Others
Protein ID: WP_015225172.1
Location: 1185120..1186133 (1014 bp)
Type: Others
Protein ID: WP_015225167.1
Location: 1186197..1186601 (405 bp)
Type: Toxin
Protein ID: WP_015225168.1
Location: 1186601..1186834 (234 bp)
Type: Antitoxin
Protein ID: WP_041596154.1
Location: 1186956..1188872 (1917 bp)
Type: Others
Protein ID: WP_015225170.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCC7418_RS054101182434..1182844+411WP_150107126.1IS200/IS605 family transposase-
PCC7418_RS054151182983..1183846+864WP_015225165.1Tab2/Atab2 family RNA-binding protein-
PCC7418_RS054201183843..1185123+1281WP_015225166.1TldD/PmbA family protein-
PCC7418_RS054251185120..1186133-1014WP_015225167.1glycerate kinase-
PCC7418_RS054301186197..1186601-405WP_015225168.1type II toxin-antitoxin system VapC family toxinToxin
PCC7418_RS054351186601..1186834-234WP_041596154.1hypothetical proteinAntitoxin
PCC7418_RS054401186956..1188872-1917WP_015225170.11-deoxy-D-xylulose-5-phosphate synthase-
PCC7418_RS054451189086..1190075+990WP_015225171.1ABC transporter ATP-binding protein-
PCC7418_RS054501190281..1191507+1227WP_015225172.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15439.14 Da        Isoelectric Point: 4.9009

>T28609 WP_015225168.1 NC_019779:c1186601-1186197 [Halothece sp. PCC 7418]
MKVLLDTNICIYIIKKQPPSVLERLQDYQVGEICISTITLYELMYGVYKSQLLEVNRQAIRQFVSPLEVLPFDEGAADWC
GYIRAILEQEGKIIGPMDLQIAAIALSYSLTLITNNEKEFKRIKQLNVENWIKL

Download         Length: 405 bp

>T28609 NC_019779:c1186601-1186197 [Halothece sp. PCC 7418]
ATGAAAGTTTTATTAGACACTAATATCTGCATCTACATTATCAAAAAGCAACCTCCATCTGTGCTAGAACGACTCCAAGA
CTATCAAGTTGGAGAGATTTGTATATCAACGATTACTCTTTATGAATTGATGTATGGGGTTTATAAAAGTCAACTTTTGG
AGGTCAATCGACAAGCAATCCGTCAGTTTGTTTCTCCTCTGGAAGTTTTACCGTTTGATGAAGGTGCTGCCGATTGGTGT
GGCTATATCCGCGCGATCTTAGAACAAGAAGGAAAAATCATTGGACCGATGGATTTACAAATTGCTGCTATAGCACTTTC
ATATAGTTTAACTTTGATCACTAATAATGAAAAAGAATTTAAACGGATTAAGCAGTTAAATGTAGAAAACTGGATTAAAT
TGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9202.34 Da        Isoelectric Point: 4.6677

>AT28609 WP_041596154.1 NC_019779:c1186834-1186601 [Halothece sp. PCC 7418]
MQYTRLSKHGYSQEVRIPRDYRLSGKRVKISRYGRGLLIEPVSEGFDDLLDSLELFSEDFLEERPEQLPFDTREDMF

Download         Length: 234 bp

>AT28609 NC_019779:c1186834-1186601 [Halothece sp. PCC 7418]
ATGCAATATACACGTCTTTCTAAGCATGGGTATTCCCAAGAAGTTAGAATTCCACGAGATTATCGACTTTCTGGAAAGCG
AGTGAAAATTTCTCGATATGGGAGAGGACTTCTCATTGAACCTGTCTCGGAGGGGTTTGATGACCTGCTGGATTCACTAG
AGTTATTTTCAGAAGATTTTCTGGAAGAACGTCCCGAACAACTTCCTTTTGATACTAGGGAAGATATGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBK9Y8M6

Antitoxin

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Source
ID
Structure
No matching records found

References