Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 3346687..3347323 Replicon chromosome
Accession NZ_LR027557
Organism Pseudomonas synxantha strain 10586

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag KR485_RS14805 Protein ID WP_082629601.1
Coordinates 3347141..3347323 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag KR485_RS14800 Protein ID WP_216090387.1
Coordinates 3346687..3347088 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KR485_RS14790 3342804..3346547 + 3744 WP_216090386.1 bifunctional diguanylate cyclase/phosphodiesterase -
KR485_RS14800 3346687..3347088 - 402 WP_216090387.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
KR485_RS14805 3347141..3347323 - 183 WP_082629601.1 type II toxin-antitoxin system HicA family toxin Toxin
KR485_RS14810 3347605..3348051 + 447 WP_216090388.1 Lrp/AsnC family transcriptional regulator -
KR485_RS14815 3348219..3349901 + 1683 WP_032881195.1 NAD(P)/FAD-dependent oxidoreductase -
KR485_RS14820 3349912..3350706 + 795 WP_032879127.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6730.85 Da        Isoelectric Point: 11.1475

>T285988 WP_082629601.1 NZ_LR027557:c3347323-3347141 [Pseudomonas synxantha]
MRSREVIDLLVADGWFEVATKGSHHQFKHPIKRGRVTVPHPKSEIAKGTLHSIFKSAGLK

Download         Length: 183 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14554.22 Da        Isoelectric Point: 4.4306

>AT285988 WP_216090387.1 NZ_LR027557:c3347088-3346687 [Pseudomonas synxantha]
MKFPVVVHKDADSDYSVTVPDVPGCFSAGSSFSEALDNVREALALHLEGLVADEETLPQAQEVDAHLENPDYAGGVWAIV
DFDLAPYLGKSVRFNASLPEQLLHRIDERVQKDHRYASRSGFLATAALRELSA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References