285987

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 1919612..1920215 Replicon chromosome
Accession NZ_LR027557
Organism Pseudomonas synxantha strain 10586

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag KR485_RS08315 Protein ID WP_216091866.1
Coordinates 1919612..1919953 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag KR485_RS08320 Protein ID WP_216091867.1
Coordinates 1919967..1920215 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KR485_RS28320 1914682..1914965 - 284 Protein_1647 tyrosine-type recombinase/integrase -
KR485_RS08295 1915277..1916941 + 1665 WP_216091863.1 colicin-like pore-forming protein -
KR485_RS08300 1917019..1917579 + 561 WP_216091864.1 hypothetical protein -
KR485_RS08305 1917790..1918749 - 960 WP_216091865.1 tyrosine-type recombinase/integrase -
KR485_RS08310 1918734..1919294 - 561 WP_248130019.1 N-acetyltransferase -
KR485_RS08315 1919612..1919953 - 342 WP_216091866.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KR485_RS08320 1919967..1920215 - 249 WP_216091867.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KR485_RS08325 1920417..1920749 - 333 WP_216091868.1 stability/partitioning determinant -
KR485_RS08330 1921089..1921421 + 333 WP_216091869.1 hypothetical protein -
KR485_RS08335 1921440..1921682 + 243 WP_216091870.1 hypothetical protein -
KR485_RS08340 1921784..1922131 + 348 WP_197880951.1 hypothetical protein -
KR485_RS08345 1922223..1922552 + 330 WP_216091871.1 hypothetical protein -
KR485_RS08350 1922569..1922775 + 207 WP_216091872.1 hypothetical protein -
KR485_RS08355 1922792..1923394 + 603 WP_216091873.1 hypothetical protein -
KR485_RS08360 1923667..1923822 + 156 WP_197880954.1 hypothetical protein -
KR485_RS08365 1923922..1924221 + 300 Protein_1662 DUF4158 domain-containing protein -
KR485_RS08370 1924636..1924887 + 252 Protein_1663 hypothetical protein -
KR485_RS08375 1924878..1925073 + 196 Protein_1664 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1902293..1927435 25142
- flank IS/Tn - - 1924009..1924254 245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-99)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12965.82 Da        Isoelectric Point: 5.4880

>T285987 WP_216091866.1 NZ_LR027557:c1919953-1919612 [Pseudomonas synxantha]
MTTLTIRYTEIAQQSIEDQVEHLAEYHSLDYALHRLDTVIDVLQKKLLSTPLGYPISSQASELGILHYRELNTDGYRVFY
EIVEADQAIVVALVLRDKQSVEKALVRHCLLHT

Download         Length: 342 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9400.84 Da        Isoelectric Point: 9.8192

>AT285987 WP_216091867.1 NZ_LR027557:c1920215-1919967 [Pseudomonas synxantha]
MRVETVSFLKKYASDLPLDEPMVVTQNGVPAYVVESYAEHKRRDETVALVKLLAMSSRQYAQGKHCSTDELKARMSRRFA
HK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References