Detailed information of TA system TA028596

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 4359494..4360091
• Replicon: chromosome
• Accession: NC_019771
• Organism: Anabaena cylindrica PCC 7122

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K9ZLL3
• Locus tag: ANACY_RS18860
• Protein ID: WP_015215816.1
• Coordinates: 4359494..4359856 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: K9ZJ29
• Locus tag: ANACY_RS18865
• Protein ID: WP_015215817.1
• Coordinates: 4359846..4360091 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ANACY_RS18845	4357180..4358145	+	966	WP_015215814.1	glycosyltransferase	-
ANACY_RS18850	4358192..4358659	-	468	WP_015215815.1	DUF29 domain-containing protein	-
ANACY_RS18855	4359029..4359343	+	315	Protein_3747	site-specific DNA-methyltransferase	-
ANACY_RS18860	4359494..4359856	-	363	WP_015215816.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ANACY_RS18865	4359846..4360091	-	246	WP_015215817.1	hypothetical protein	Antitoxin
ANACY_RS18870	4360354..4361148	+	795	WP_015215818.1	30S ribosomal protein S2	-
ANACY_RS18875	4361425..4361653	+	229	Protein_3751	IS200/IS605 family element transposase accessory protein TnpB	-
ANACY_RS18880	4361920..4362864	+	945	WP_015215819.1	elongation factor Ts	-
ANACY_RS18885	4363030..4363854	+	825	WP_015215820.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (59-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 14102.97 Da
• Isoelectric Point: 5.7761

>T28596 WP_015215816.1 NC_019771:c4359856-4359494 [Anabaena cylindrica PCC 7122]
MQNDSFLIKIDLTPEYQRNLKSLAKKYRKIRSDTQSFITELQKVHLLGDRLTGFDEDVYIYKARVKNSNIQKGKSAGYRV
IYLLESETSILLLTIYSKSEQEDITDHDINSILDEFYKDE

Nucleotide

• Length: 363 bp

>T28596 NC_019771:c4359856-4359494 [Anabaena cylindrica PCC 7122]
ATGCAGAATGATTCTTTCTTAATTAAGATTGATTTAACTCCTGAATATCAGAGAAATTTAAAATCTTTAGCTAAAAAATA
CCGGAAGATTCGTTCTGATACCCAGTCTTTCATTACAGAATTGCAAAAAGTCCATTTATTAGGAGATAGGTTAACTGGTT
TTGATGAAGATGTTTATATTTATAAAGCTAGAGTCAAAAATAGTAATATTCAAAAAGGTAAAAGTGCTGGTTATCGGGTA
ATTTATTTACTGGAATCTGAAACCAGCATTTTATTGTTAACAATTTACAGTAAATCTGAACAAGAAGATATTACTGATCA
TGATATTAATTCTATTTTAGACGAATTTTATAAAGATGAATAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9074.60 Da
• Isoelectric Point: 4.5216

>AT28596 WP_015215817.1 NC_019771:c4360091-4359846 [Anabaena cylindrica PCC 7122]
MKAFEVMGKVNEKGQLLLDKPLEIHTSSLVRVIILVLDETEFDPDDTPIVEIKASLKTALQEAKAGKRIPLEKMWEGIDA
E

Nucleotide

• Length: 246 bp

>AT28596 NC_019771:c4360091-4359846 [Anabaena cylindrica PCC 7122]
ATGAAAGCTTTTGAAGTCATGGGAAAAGTTAATGAAAAAGGTCAATTATTACTAGATAAACCTTTAGAAATTCATACGTC
TAGTCTAGTCAGAGTAATTATCCTTGTATTAGATGAAACTGAATTTGATCCTGATGATACTCCCATTGTGGAAATTAAAG
CAAGTTTAAAAACAGCATTACAAGAAGCAAAAGCAGGAAAAAGAATACCTTTAGAAAAAATGTGGGAAGGAATTGATGCA
GAATGA

Structures

Toxin

• AlphaFold DB: K9ZLL3

Antitoxin

• AlphaFold DB: K9ZJ29