Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2865576..2865847 Replicon chromosome
Accession NZ_LR025101
Organism Escherichia coli isolate EC-1639

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2865614..2865717 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2865576..2865847 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC1639_RS13880 2862733..2864172 + 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EC1639_RS13885 2864290..2864526 + 237 WP_001295499.1 DUF1480 family protein -
EC1639_RS13890 2864631..2864822 + 192 WP_001296140.1 YebW family protein -
EC1639_RS13895 2864823..2865479 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2865576..2865847 + 272 - - Antitoxin
- 2865614..2865717 - 104 - - Toxin
EC1639_RS13900 2865875..2866216 - 342 WP_000976481.1 YebY family protein -
EC1639_RS13905 2866229..2867101 - 873 WP_001587145.1 copper homeostasis membrane protein CopD -
EC1639_RS13910 2867105..2867479 - 375 WP_000168743.1 CopC domain-containing protein YobA -
EC1639_RS13915 2867618..2867848 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EC1639_RS13920 2867950..2868606 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
EC1639_RS13925 2868630..2869292 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2862727..2873157 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T285904 NZ_LR025101:c2865717-2865614 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT285904 NZ_LR025101:2865576-2865847 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References