Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3475691..3475836 | Replicon | chromosome |
| Accession | NZ_LR025099 | ||
| Organism | Klebsiella pneumoniae isolate EC-12536 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3475698..3475800 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3475691..3475836 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EC12536_RS17270 | 3471223..3472656 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| EC12536_RS17275 | 3472772..3473011 | + | 240 | WP_002911393.1 | YebV family protein | - |
| EC12536_RS17280 | 3473109..3473300 | + | 192 | WP_002911395.1 | YebW family protein | - |
| EC12536_RS17285 | 3473297..3473950 | - | 654 | WP_032415192.1 | protein-serine/threonine phosphatase | - |
| EC12536_RS17290 | 3474107..3475075 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| EC12536_RS26900 | 3475180..3475323 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 3475691..3475836 | + | 146 | - | - | Antitoxin |
| - | 3475698..3475800 | - | 103 | - | - | Toxin |
| EC12536_RS17300 | 3475959..3476297 | - | 339 | WP_002911404.1 | YebY family protein | - |
| EC12536_RS17305 | 3476314..3477183 | - | 870 | WP_134156359.1 | copper homeostasis membrane protein CopD | - |
| EC12536_RS17310 | 3477187..3477561 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| EC12536_RS17315 | 3477674..3477904 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| EC12536_RS17320 | 3477983..3478642 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| EC12536_RS17325 | 3478646..3480706 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T285877 NZ_LR025099:c3475800-3475698 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT285877 NZ_LR025099:3475691-3475836 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
