Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 673699..674519 Replicon chromosome
Accession NZ_LR025096
Organism Escherichia coli isolate EC-7215

Toxin (Protein)


Gene name yjhX Uniprot ID B6I030
Locus tag EC7215_RS03225 Protein ID WP_001054379.1
Coordinates 674262..674519 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag EC7215_RS03220 Protein ID WP_000123957.1
Coordinates 673699..674250 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC7215_RS03195 669393..670706 - 1314 WP_000460845.1 galactitol-specific PTS transporter subunit IIC -
EC7215_RS03200 670718..670996 - 279 WP_000722973.1 PTS sugar transporter subunit IIB -
EC7215_RS03205 670993..672114 - 1122 WP_000010833.1 M42 family metallopeptidase -
EC7215_RS24905 672359..672475 - 117 Protein_600 VOC family protein -
EC7215_RS03210 672513..672773 - 261 WP_000077646.1 hypothetical protein -
EC7215_RS03215 672901..673647 - 747 WP_000354249.1 class I SAM-dependent methyltransferase -
EC7215_RS03220 673699..674250 - 552 WP_000123957.1 N-acetyltransferase Antitoxin
EC7215_RS03225 674262..674519 - 258 WP_001054379.1 YjhX family toxin Toxin
EC7215_RS03230 674896..675195 - 300 WP_001332034.1 GNAT family N-acetyltransferase -
EC7215_RS03235 675273..676499 + 1227 Protein_606 helicase YjhR -
EC7215_RS03240 677082..678062 - 981 WP_000991462.1 9-O-acetyl-N-acetylneuraminic acid deacetylase -
EC7215_RS03245 678126..679232 - 1107 WP_001295733.1 N-acetylneuraminate epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(19-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T285851 WP_001054379.1 NZ_LR025096:c674519-674262 [Escherichia coli]
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20358.34 Da        Isoelectric Point: 6.4182

>AT285851 WP_000123957.1 NZ_LR025096:c674250-673699 [Escherichia coli]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B6I030

Antitoxin

Source ID Structure

References