Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2951955..2952100 Replicon chromosome
Accession NZ_LR025092
Organism Klebsiella pneumoniae isolate KP9201

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2951962..2952064 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2951955..2952100 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP920_RS14940 2947486..2948919 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KP920_RS14945 2949035..2949274 + 240 WP_002911393.1 YebV family protein -
KP920_RS14950 2949372..2949563 + 192 WP_002911395.1 YebW family protein -
KP920_RS14955 2949560..2950213 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
KP920_RS14960 2950370..2951338 + 969 WP_004151446.1 VirK/YbjX family protein -
KP920_RS28330 2951443..2951586 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2951955..2952100 + 146 - - Antitoxin
- 2951962..2952064 - 103 - - Toxin
KP920_RS14970 2952223..2952561 - 339 WP_009307539.1 YebY family protein -
KP920_RS14975 2952578..2953447 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
KP920_RS14980 2953451..2953825 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KP920_RS14985 2953938..2954168 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KP920_RS14990 2954247..2954906 + 660 WP_002911407.1 exodeoxyribonuclease X -
KP920_RS14995 2954910..2956970 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T285836 NZ_LR025092:c2952064-2951962 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT285836 NZ_LR025092:2951955-2952100 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References