Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1928450..1928595 Replicon chromosome
Accession NZ_LR025088
Organism Klebsiella pneumoniae isolate KP980

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1928457..1928559 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1928450..1928595 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP980_RS09845 1923981..1925414 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KP980_RS09850 1925530..1925769 + 240 WP_002911393.1 YebV family protein -
KP980_RS09855 1925867..1926058 + 192 WP_002911395.1 YebW family protein -
KP980_RS09860 1926055..1926708 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
KP980_RS09865 1926865..1927833 + 969 WP_004151446.1 VirK/YbjX family protein -
KP980_RS28575 1927938..1928081 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1928450..1928595 + 146 - - Antitoxin
- 1928457..1928559 - 103 - - Toxin
KP980_RS09875 1928718..1929056 - 339 WP_009307539.1 YebY family protein -
KP980_RS09880 1929073..1929942 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
KP980_RS09885 1929946..1930320 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KP980_RS09890 1930433..1930663 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KP980_RS09895 1930742..1931401 + 660 WP_002911407.1 exodeoxyribonuclease X -
KP980_RS09900 1931405..1933465 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T285817 NZ_LR025088:c1928559-1928457 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT285817 NZ_LR025088:1928450-1928595 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References