285809

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1223459..1224376 Replicon chromosome
Accession NZ_LN999829
Organism Bacillus velezensis strain B25

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A6A8LGT8
Locus tag BAMMD1_RS06170 Protein ID WP_003154806.1
Coordinates 1223630..1224376 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag BAMMD1_RS06165 Protein ID WP_060386896.1
Coordinates 1223459..1223629 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAMMD1_RS06130 1218691..1220313 + 1623 WP_024085192.1 pyocin knob domain-containing protein -
BAMMD1_RS06135 1220326..1220697 + 372 WP_024085193.1 hypothetical protein -
BAMMD1_RS06140 1220703..1220900 + 198 WP_003154819.1 XkdX family protein -
BAMMD1_RS06145 1220957..1221718 + 762 WP_024085194.1 hypothetical protein -
BAMMD1_RS06150 1221770..1222033 + 264 WP_032866112.1 hemolysin XhlA family protein -
BAMMD1_RS06155 1222047..1222310 + 264 WP_003154813.1 phage holin -
BAMMD1_RS06160 1222324..1223202 + 879 WP_024085195.1 N-acetylmuramoyl-L-alanine amidase -
BAMMD1_RS06165 1223459..1223629 - 171 WP_060386896.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
BAMMD1_RS06170 1223630..1224376 - 747 WP_003154806.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
BAMMD1_RS06175 1224481..1225479 - 999 WP_003154805.1 inorganic phosphate transporter -
BAMMD1_RS06180 1225492..1226109 - 618 WP_003154804.1 DUF47 domain-containing protein -
BAMMD1_RS06185 1226395..1227711 - 1317 WP_046559522.1 amino acid permease -
BAMMD1_RS06190 1228035..1228985 + 951 WP_060386897.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29034.50 Da        Isoelectric Point: 4.6947

>T285809 WP_003154806.1 NZ_LN999829:c1224376-1223630 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYGEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQDRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6666.70 Da        Isoelectric Point: 10.9273

>AT285809 WP_060386896.1 NZ_LN999829:c1223629-1223459 [Bacillus velezensis]
MEQAFQNGQPEQRAKSFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6A8LGT8

Antitoxin

Source ID Structure

References