Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-higA/PemK-HTH_31
Location 4562093..4562615 Replicon chromosome
Accession NZ_LN997848
Organism Magnetospirillum sp. XM-1 isolate XM1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag XM1_RS24320 Protein ID WP_156428882.1
Coordinates 4562093..4562275 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0U5MQG7
Locus tag XM1_RS20920 Protein ID WP_068436916.1
Coordinates 4562334..4562615 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XM1_RS20890 4557280..4557546 + 267 WP_068436902.1 hypothetical protein -
XM1_RS20895 4557896..4558792 - 897 WP_068436904.1 LOG family protein -
XM1_RS20900 4558942..4559598 + 657 WP_068436906.1 MBL fold metallo-hydrolase -
XM1_RS20905 4559611..4560450 - 840 WP_068436912.1 hypothetical protein -
XM1_RS23645 4561126..4561389 + 264 WP_156428813.1 DNA-binding protein -
XM1_RS24320 4562093..4562275 + 183 WP_156428882.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
XM1_RS20920 4562334..4562615 + 282 WP_068436916.1 helix-turn-helix domain-containing protein Antitoxin
XM1_RS24325 4562640..4564103 - 1464 WP_156428814.1 hypothetical protein -
XM1_RS24330 4564122..4564439 - 318 WP_156428815.1 AAA family ATPase -
XM1_RS20930 4564528..4565643 - 1116 WP_068436920.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-57)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-82)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6585.70 Da        Isoelectric Point: 7.9949

>T285804 WP_156428882.1 NZ_LN997848:4562093-4562275 [Magnetospirillum sp. XM-1]
MCDRLTVSPTPDNGLRKVSQIMVDKTMTVNRDKLGEVFGRIDDGTMVAVNRALALFLGFA

Download         Length: 183 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10107.41 Da        Isoelectric Point: 7.0157

>AT285804 WP_068436916.1 NZ_LN997848:4562334-4562615 [Magnetospirillum sp. XM-1]
VSSLKDLKERLLADPATRAEYEAQPPEFEIAEELIRARQRAGLSQAEVARRMGTTQSVVARLESGRSMPSAASLSRYAAA
TGSRLHVELVPAE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0U5MQG7

References