Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 180163..180983 Replicon chromosome
Accession NZ_LN997848
Organism Magnetospirillum sp. XM-1 isolate XM1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag XM1_RS22955 Protein ID WP_082700309.1
Coordinates 180163..180678 (-) Length 172 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A0U5MDB5
Locus tag XM1_RS00895 Protein ID WP_068428319.1
Coordinates 180687..180983 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XM1_RS00875 176112..177017 + 906 WP_068428311.1 U32 family peptidase -
XM1_RS00880 177129..178139 + 1011 WP_068428314.1 hypothetical protein -
XM1_RS00890 178502..179926 + 1425 WP_156428601.1 site-specific integrase -
XM1_RS22955 180163..180678 - 516 WP_082700309.1 GNAT family N-acetyltransferase Toxin
XM1_RS00895 180687..180983 - 297 WP_068428319.1 DUF1778 domain-containing protein Antitoxin
XM1_RS23785 180986..181591 - 606 WP_156428602.1 hypothetical protein -
XM1_RS00905 182000..182350 + 351 WP_068428324.1 hypothetical protein -
XM1_RS00910 182363..182998 - 636 WP_068428327.1 recombinase family protein -
XM1_RS23790 183104..183391 + 288 WP_156428603.1 hypothetical protein -
XM1_RS00915 183943..184200 + 258 WP_068428329.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(12-84)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18103.92 Da        Isoelectric Point: 9.2825

>T285803 WP_082700309.1 NZ_LN997848:c180678-180163 [Magnetospirillum sp. XM-1]
MALSAPEPLNAGHDVSQFSCGKPALDHWLKTRALSNQERGFTVVMVVHDAGRVIGYYGLAPTAVLPTAMPRSIKTGQPPN
PVPCLLLGQLATDQGWAGQGIGTGLLAHALTRCVQGAKLIGGRALIVNAIDPDAASFWRRRGFLPSKDDQLVLFRSIADI
AASLDAGEVRK

Download         Length: 516 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10642.23 Da        Isoelectric Point: 6.4674

>AT285803 WP_068428319.1 NZ_LN997848:c180983-180687 [Magnetospirillum sp. XM-1]
MAPTAHRKDHPLSMRLPDTDIALIDRAAGLRGRSRTDFVREAAVRAAEEVLMESGLIRMSQEGFAEFMAVLSAPATVVAP
MVEVLRRPAPWDQGSGQG

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0U5MDB5

References