Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 596290..596765 Replicon chromosome
Accession NZ_LN907867
Organism Blastochloris viridis isolate

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag BVIRIDIS_RS02615 Protein ID WP_055038701.1
Coordinates 596290..596481 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID A0A0P0ID03
Locus tag BVIRIDIS_RS02620 Protein ID WP_055036760.1
Coordinates 596478..596765 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVIRIDIS_RS02580 591795..592097 - 303 WP_055038700.1 hypothetical protein -
BVIRIDIS_RS02585 592331..593386 - 1056 WP_082417334.1 polysaccharide deacetylase family protein -
BVIRIDIS_RS02590 594040..594255 + 216 WP_055036755.1 hypothetical protein -
BVIRIDIS_RS02595 594321..594611 - 291 WP_055036756.1 hypothetical protein -
BVIRIDIS_RS02600 594771..595211 + 441 WP_055036757.1 isoprenylcysteine carboxylmethyltransferase family protein -
BVIRIDIS_RS02605 595264..595593 - 330 WP_058124826.1 hypothetical protein -
BVIRIDIS_RS02610 595838..596185 + 348 WP_055036759.1 ArsC family reductase -
BVIRIDIS_RS02615 596290..596481 + 192 WP_055038701.1 type II toxin-antitoxin system HicA family toxin Toxin
BVIRIDIS_RS02620 596478..596765 + 288 WP_055036760.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
BVIRIDIS_RS16610 597236..597679 - 444 WP_145911850.1 hypothetical protein -
BVIRIDIS_RS02625 597738..597986 - 249 WP_055036761.1 DUF2442 domain-containing protein -
BVIRIDIS_RS16615 598298..598810 - 513 WP_145911849.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(5-86)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7255.39 Da        Isoelectric Point: 10.9847

>T285793 WP_055038701.1 NZ_LN907867:596290-596481 [Blastochloris viridis]
IDSRDIIRLLEQDGWIYVGATGSHYHFRHPAKPGKVTVPHPRKDLHPKTARSIFRMAGLKEPR

Download         Length: 192 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 9564.56 Da        Isoelectric Point: 3.9005

>AT285793 WP_055036760.1 NZ_LN907867:596478-596765 [Blastochloris viridis]
MMAGYLALVHKDAGTSYGVSFPDVPGCVSAGDTLEEALANAAEALGGHLALLATDGDSVPSPRSFEALRADASLADEFED
AVVSFVQPHATASAA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0P0ID03

References