Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2293608..2294149 Replicon chromosome
Accession NZ_LN907827
Organism Erwinia gerundensis isolate E_g_EM595

Toxin (Protein)


Gene name relE Uniprot ID A0A0U5L7E3
Locus tag EM595_RS10700 Protein ID WP_067431537.1
Coordinates 2293862..2294149 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0U5L6M5
Locus tag EM595_RS10695 Protein ID WP_067431534.1
Coordinates 2293608..2293856 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EM595_RS10675 2288709..2289287 - 579 WP_067431528.1 flagellar transcriptional regulator FlhC -
EM595_RS10680 2289284..2289640 - 357 WP_067431531.1 flagellar transcriptional regulator FlhD -
EM595_RS10685 2290707..2292143 - 1437 WP_067431533.1 alpha,alpha-trehalose-phosphate synthase -
EM595_RS10690 2292148..2292921 - 774 WP_157883920.1 trehalose-phosphatase -
EM595_RS10695 2293608..2293856 + 249 WP_067431534.1 antitoxin Antitoxin
EM595_RS10700 2293862..2294149 + 288 WP_067431537.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EM595_RS10705 2294178..2295437 - 1260 WP_067431540.1 translesion error-prone DNA polymerase V subunit UmuC -
EM595_RS10710 2295912..2296586 - 675 WP_067431543.1 hypothetical protein -
EM595_RS10715 2296804..2297211 - 408 WP_173645372.1 DNA polymerase V subunit UmuD -
EM595_RS10720 2297513..2298592 - 1080 WP_067431546.1 two-component system sensor histidine kinase PmrB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10968.00 Da        Isoelectric Point: 10.5498

>T285789 WP_067431537.1 NZ_LN907827:2293862-2294149 [Erwinia gerundensis]
MGYTIKIREEALKEWNGLDSIIREQFKKKLKKPPENPHIPAARLAGMPDCYKIKLRASGFRLVYQVMDDVLIVAVVAVGK
RERSQPYKLASERLR

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9056.45 Da        Isoelectric Point: 4.0927

>AT285789 WP_067431534.1 NZ_LN907827:2293608-2293856 [Erwinia gerundensis]
MANLILSDTSASVSELKKNPMATVEAGAGMPVTILNRNQPVFYCVPAHLYEKMLEIIDDQELATLVKARENQPLLDLDLD
LD

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0U5L7E3

Antitoxin

Source ID Structure
AlphaFold DB A0A0U5L6M5

References