Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 4278331..4278933 Replicon chromosome
Accession NZ_LN901633
Organism Bradyrhizobium sp. isolate BF49_genome1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BN2626_RS20165 Protein ID WP_063994642.1
Coordinates 4278634..4278933 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H5YDN2
Locus tag BN2626_RS20160 Protein ID WP_007605286.1
Coordinates 4278331..4278630 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2626_RS20140 4274233..4274664 - 432 WP_007605278.1 acyl-CoA thioesterase -
BN2626_RS20145 4274675..4275436 - 762 WP_063994641.1 SDR family NAD(P)-dependent oxidoreductase -
BN2626_RS20150 4275458..4277344 - 1887 WP_007605283.1 feruloyl-CoA synthase -
BN2626_RS20155 4277341..4278150 - 810 WP_007605285.1 crotonase/enoyl-CoA hydratase family protein -
BN2626_RS20160 4278331..4278630 - 300 WP_007605286.1 putative addiction module antidote protein Antitoxin
BN2626_RS20165 4278634..4278933 - 300 WP_063994642.1 addiction module protein Toxin
BN2626_RS20170 4279001..4279462 - 462 WP_063994643.1 DUF3237 domain-containing protein -
BN2626_RS20175 4279474..4280793 - 1320 WP_007599671.1 TRAP transporter permease -
BN2626_RS20180 4280796..4281305 - 510 WP_007605289.1 TRAP transporter small permease -
BN2626_RS20185 4281439..4282455 - 1017 WP_063994644.1 TRAP transporter substrate-binding protein -
BN2626_RS20190 4282670..4283839 + 1170 WP_063994645.1 4-hydroxybenzoate 3-monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-98)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10881.57 Da        Isoelectric Point: 10.8536

>T285786 WP_063994642.1 NZ_LN901633:c4278933-4278634 [Bradyrhizobium sp.]
MPTIKRTDEFSDWLRNLRDRRAKAKILARIDRLALGNPGDVAPVGGGISEMRVHEGAGYRIYYVAPRARRSLFSFAGAIK
GSQPGDIALAKKIASELEV

Download         Length: 300 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10334.80 Da        Isoelectric Point: 4.7513

>AT285786 WP_007605286.1 NZ_LN901633:c4278630-4278331 [Bradyrhizobium sp.]
MAKVKSFDAAEYLDSPEMIAAYLTEAFESDDPSAITMAIGAVARSQGMGAIAEKAGLSRENLYRSLGGEAKPEFGTVIKV
LHAMGINLVAQPQSGTKAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB H5YDN2

References