Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1108914..1109533 Replicon chromosome
Accession NZ_LN901633
Organism Bradyrhizobium sp. isolate BF49_genome1

Toxin (Protein)


Gene name vapC Uniprot ID A0A160U8A9
Locus tag BN2626_RS05235 Protein ID WP_063992768.1
Coordinates 1109141..1109533 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BN2626_RS05230 Protein ID WP_035974028.1
Coordinates 1108914..1109144 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2626_RS05205 1103980..1104639 + 660 WP_063992766.1 hypothetical protein -
BN2626_RS05210 1104710..1105552 + 843 WP_007609144.1 metallophosphoesterase -
BN2626_RS05215 1105569..1105865 - 297 WP_084777575.1 hypothetical protein -
BN2626_RS05220 1106017..1107039 - 1023 WP_007609140.1 NADP-dependent oxidoreductase -
BN2626_RS05225 1107160..1108650 - 1491 WP_007609139.1 IMP dehydrogenase -
BN2626_RS05230 1108914..1109144 + 231 WP_035974028.1 hypothetical protein Antitoxin
BN2626_RS05235 1109141..1109533 + 393 WP_063992768.1 type II toxin-antitoxin system VapC family toxin Toxin
BN2626_RS05240 1109694..1111184 + 1491 WP_063992769.1 MFS transporter -
BN2626_RS05245 1111289..1111978 - 690 WP_007609132.1 RlmE family RNA methyltransferase -
BN2626_RS05250 1111980..1113047 - 1068 WP_063996565.1 Ppx/GppA family phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Pae0151-like, PIN domain

(3-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14569.80 Da        Isoelectric Point: 6.7603

>T285784 WP_063992768.1 NZ_LN901633:1109141-1109533 [Bradyrhizobium sp.]
VIVVDASALLEVLLRTPAAATVEQRLFAPHQTLHAPHLLDVEVAQVIRRYAANREINVERGRMALADLADLSLRRYPHDF
LLPRIWELRNNLTAYDAAYVALAEALDTPLLTRDRRLAAAPGHHAQIELV

Download         Length: 393 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8630.98 Da        Isoelectric Point: 11.5079

>AT285784 WP_035974028.1 NZ_LN901633:1108914-1109144 [Bradyrhizobium sp.]
MTTMIQIRNVPDALHRRLKSRAALAGMSLSDYLLSEIRQVAERPTLDELRARLRSRTETMPSIAPAEAVRAERDRA

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A160U8A9

Antitoxin

Source ID Structure

References