Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_XRE
Location 3400937..3401562 Replicon chromosome
Accession NZ_LN890655
Organism Candidatus Promineofilum breve strain Cfx-K

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CFX0092_RS14735 Protein ID WP_095044272.1
Coordinates 3400937..3401194 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFX0092_RS14740 Protein ID WP_095044273.1
Coordinates 3401191..3401562 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFX0092_RS14725 3398428..3398820 - 393 WP_095044270.1 glycine cleavage system protein GcvH -
CFX0092_RS14730 3399515..3400867 + 1353 WP_095044271.1 aspartate aminotransferase family protein -
CFX0092_RS14735 3400937..3401194 + 258 WP_095044272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFX0092_RS14740 3401191..3401562 + 372 WP_095044273.1 helix-turn-helix transcriptional regulator Antitoxin
CFX0092_RS22330 3401635..3401877 + 243 WP_157913197.1 hypothetical protein -
CFX0092_RS14745 3401898..3403085 + 1188 WP_095044274.1 alanine racemase -
CFX0092_RS14750 3403277..3403693 + 417 WP_095044275.1 OsmC family protein -
CFX0092_RS14755 3403706..3404164 + 459 WP_095044276.1 hypothetical protein -
CFX0092_RS14760 3404207..3405013 + 807 WP_095042622.1 IS5 family transposase -
CFX0092_RS14765 3405024..3406019 + 996 WP_095044277.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3404207..3405013 806


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Cro/C1-type helix-turn-helix domain

(67-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9917.68 Da        Isoelectric Point: 10.8225

>T285782 WP_095044272.1 NZ_LN890655:3400937-3401194 [Candidatus Promineofilum breve]
MYQVSFSKEAQKALLKLPRPLALKIREKLTAVARDPYAQHNNVSKLQNRPGYRLRIGDWRVIYEIRGDELVILVVKIAPR
GEVYR

Download         Length: 258 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13358.15 Da        Isoelectric Point: 3.8846

>AT285782 WP_095044273.1 NZ_LN890655:3401191-3401562 [Candidatus Promineofilum breve]
MSIQLILKEGQPEYAVLPYETYLRLVEDAEMLADVRDYDAAIQAIAEGEELIPAEVVYALLDGANPIRVWREYRGLSQGE
LAAKVGISPSYLSQLESGKRDGTMEVLSAVAAALDVTLDDLAG

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References