Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-Phd
Location 2421311..2421816 Replicon chromosome
Accession NZ_LN890655
Organism Candidatus Promineofilum breve strain Cfx-K

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CFX0092_RS10475 Protein ID WP_095044882.1
Coordinates 2421311..2421577 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFX0092_RS10480 Protein ID WP_095043479.1
Coordinates 2421574..2421816 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFX0092_RS10455 2417303..2418049 + 747 WP_157913069.1 c-type cytochrome -
CFX0092_RS10460 2418028..2419188 + 1161 WP_095043476.1 hypothetical protein -
CFX0092_RS10465 2419268..2420329 + 1062 WP_095043477.1 ABC transporter permease -
CFX0092_RS10470 2420331..2421308 + 978 WP_095043478.1 ABC transporter permease -
CFX0092_RS10475 2421311..2421577 - 267 WP_095044882.1 Txe/YoeB family addiction module toxin Toxin
CFX0092_RS10480 2421574..2421816 - 243 WP_095043479.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CFX0092_RS10485 2422004..2422315 + 312 WP_095043480.1 hypothetical protein -
CFX0092_RS10490 2422316..2422696 + 381 WP_095043481.1 hypothetical protein -
CFX0092_RS10495 2422736..2423764 - 1029 WP_095043482.1 C40 family peptidase -
CFX0092_RS10500 2423861..2424892 - 1032 WP_095043483.1 dipeptide epimerase -
CFX0092_RS10505 2424992..2426131 - 1140 WP_095043484.1 M20 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10249.87 Da        Isoelectric Point: 10.4492

>T285780 WP_095044882.1 NZ_LN890655:c2421577-2421311 [Candidatus Promineofilum breve]
VTAWRVVFTKQAQKDAKKLSAANLRPKAEASLAILREDPYRTPPPFEKLVGDLSGAYSRRINVQHRLVYQVLDEERVVKV
IRMWTHYE

Download         Length: 267 bp

>T285780 NZ_LN890655:c2421577-2421311 [Candidatus Promineofilum breve]
GTGACGGCCTGGCGCGTCGTCTTCACCAAACAGGCGCAAAAAGACGCCAAGAAACTGTCCGCAGCCAATCTGCGCCCCAA
GGCCGAAGCGTCATTGGCGATTCTCCGCGAAGACCCTTACCGCACGCCCCCGCCATTTGAAAAGCTGGTTGGCGACCTGA
GCGGGGCCTATTCGCGGCGCATCAACGTGCAGCATCGCCTGGTTTATCAGGTGCTGGATGAAGAGCGAGTGGTCAAGGTG
ATTCGTATGTGGACCCACTACGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8783.98 Da        Isoelectric Point: 4.0075

>AT285780 WP_095043479.1 NZ_LN890655:c2421816-2421574 [Candidatus Promineofilum breve]
MTTLTATEARANLYKLLDEIAATHEPVLITGKRANAVLISEDDWRAIEETIYLLGIPGMRESIIEGLATPPDECADGVEW

Download         Length: 243 bp

>AT285780 NZ_LN890655:c2421816-2421574 [Candidatus Promineofilum breve]
ATGACCACCCTGACCGCCACCGAAGCCCGCGCCAACCTGTATAAGCTCCTCGATGAGATCGCGGCCACCCACGAACCGGT
GCTGATAACCGGCAAGCGGGCCAATGCCGTCCTGATTTCGGAAGACGATTGGCGGGCCATCGAGGAGACGATTTATCTGC
TCGGGATTCCGGGTATGCGCGAGTCGATCATCGAGGGTCTGGCGACGCCGCCGGACGAGTGCGCCGACGGGGTTGAGTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References