Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 59174..59733 Replicon plasmid 2
Accession NZ_LN890525
Organism Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385

Toxin (Protein)


Gene name relE Uniprot ID U9YB49
Locus tag ARA94_RS24385 Protein ID WP_000421259.1
Coordinates 59458..59733 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U9Y625
Locus tag ARA94_RS24380 Protein ID WP_001178087.1
Coordinates 59174..59458 (+) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ARA94_RS24360 54823..55356 - 534 WP_001372168.1 transcription termination factor NusG -
ARA94_RS24365 55798..56085 - 288 WP_000074849.1 conjugal transfer protein TraA -
ARA94_RS26500 56003..56266 - 264 WP_001324596.1 ash family protein -
ARA94_RS24375 57239..58270 + 1032 WP_000907852.1 replication initiation protein -
ARA94_RS24380 59174..59458 + 285 WP_001178087.1 ribbon-helix-helix protein, CopG family Antitoxin
ARA94_RS24385 59458..59733 + 276 WP_000421259.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ARA94_RS24390 59839..60120 + 282 WP_001105066.1 hypothetical protein -
ARA94_RS24395 60312..60578 - 267 WP_000627832.1 hypothetical protein -
ARA94_RS24400 60578..61072 - 495 WP_015058884.1 hypothetical protein -
ARA94_RS24405 61128..61730 - 603 WP_000521606.1 hypothetical protein -
ARA94_RS24410 61906..62958 - 1053 WP_000655519.1 hypothetical protein -
ARA94_RS24415 63171..63761 - 591 WP_053289960.1 hypothetical protein -
ARA94_RS24420 63761..64015 - 255 WP_000343106.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..84987 84987


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T285777 WP_000421259.1 NZ_LN890525:59458-59733 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp


Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT285777 WP_001178087.1 NZ_LN890525:59174-59458 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB U9YB49


Antitoxin

Source ID Structure
AlphaFold DB U9Y625

References